Abstract: A metered dose inhaler canister combination includes a canister constructed for containing a pharmaceutical composition, the canister having a canister base, a side wall extending from the canister base, an open end distal from the base and a first cooperating formation arranged at the open end and extending generally distally from the canister base; a shroud having a shroud base and a side wall extending from the shroud base to a waist, the base and side wall defining a vessel constructed to receive the canister therein, the waist defining an aperture of constricted width constructed to receive the canister therethrough, and a second cooperating formation extending generally distally from the waist, wherein the respective first and second cooperating formations adopt an engaged condition in which the canister is retained within the shroud.

Abstract: A method of forming a hollow article (2) comprises the steps of providing a metal blank in the form of a disk. Subsequently, a metal blank is transferred to a first forming station which comprises a punch and a die. A metal blank is formed into a cup having a sidewall and a closed base. A boundary lubrication is provided between the die and the metal blank by application of a lubricant. Hereinafter, the metal cup is provided to a set of forming stations in a deep drawing transfer press. The set of forming stations comprises at least one set of punches and dies. Said metal cup is deep drawn into a hollow article (2) having a sidewall (4) and a closed base (7) with an inner and an outer surface (, 8, 6, 9) by the action of said at least one set of punches and dies. Subsequently, the hollow article (2) is provided to a subsequent forming station in the deep drawing transfer press.

Abstract: A metered dose inhaler canister combination comprises a canister configured for containing a pharmaceutical composition, the canister having a canister base, a side wall extending from the canister base, an open end distal from the base and a first cooperating formation arranged at said open end and extending generally distally from said canister base; a shroud having a shroud base and a side wall extending from the shroud base to a waist, the base and side wall defining a vessel configured to receive the canister therein, the waist defining an aperture of constricted width configured to receive the canister therethrough, and a second cooperating formation extending generally distally from said waist, wherein the respective first and second cooperating formations adopt an engaged condition in which the canister is retained within the shroud.