Patents by Inventor Alana Lea GRAY

Alana Lea GRAY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemicals and methods to prevent and treat TGF-beta mediated activation of fibroblasts to reduce and treat cancer and fibrosis
    Patent number: 11096952
    Abstract: A method of treating an activated fibroblast associated disease or pre-disease condition in a mammal comprising, administering a pharmaceutical composition including a therapeutically effective amount of a first therapeutic, wherein the first therapeutic is one of an intracellular Ca2+ elevator, a YAP/TAZ inhibitor, both a intracellular Ca2+ elevator and a YAP/TAZ inhibitor, or pharmacologically acceptable salts, solvates, esters, amides, clathrates, stereoisomers, enantiomers, prodrugs or analogs thereof, or a combination thereof.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: August 24, 2021
    Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
    Inventors: James Allen Cardelli, Charles Albert Stephens, Alana Lea Gray, David Thomas Coleman
  • Isothiocyanatostilbenes as a novel method and product for treating cancer
    Patent number: 10980765
    Abstract: Products and methods for treating cancer in a human patient comprising administering to the patient therapeutically effective amount of a first pharmaceutically active agent, wherein the first pharmaceutically active agent is one of an isothiocyanatostilbene and a pharmacologically acceptable salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, prodrug or analog thereof, or a combination thereof.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: April 20, 2021
    Assignees: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY, BOARD OF SUPERVISORS FOR THE UNIVERSITY OF LOUISIA
    Inventors: Alana Lea Gray, James Cardelli, David Thomas Coleman, Khalid El-Sayed, Mohamed M. Mohyeldin
  • CHEMICALS AND METHODS TO PREVENT AND TREAT TGF-BETA MEDIATED ACTIVATION OF FIBROBLASTS TO REDUCE AND TREAT CANCER AND FIBROSIS
    Publication number: 20190038655
    Abstract: A method of treating an activated fibroblast associated disease or pre-disease condition in a mammal comprising, administering a pharmaceutical composition including a therapeutically effective amount of a first therapeutic, wherein the first therapeutic is one of an intracellular Ca2+ elevator, a YAP/TAZ inhibitor, both a intracellular Ca2+ elevator and a YAP/TAZ inhibitor, or pharmacologically acceptable salts, solvates, esters, amides, clathrates, stereoisomers, enantiomers, prodrugs or analogs thereof, or a combination thereof.
    Type: Application
    Filed: February 2, 2017
    Publication date: February 7, 2019
    Inventors: James Allen CARDELLI, Charles Albert STEPHENS, Alana Lea GRAY, David Thomas COLEMAN
  • ISOTHIOCYANATOSTILBENES AS A NOVEL METHOD AND PRODUCT FOR TREATING CANCER
    Publication number: 20190000791
    Abstract: Products and methods for treating cancer in a human patient comprising administering to the patient therapeutically effective amount of a first pharmaceutically active agent, wherein the first pharmaceutically active agent is one of an isothiocyanatostilbene and a pharmacologically acceptable salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, prodrug or analog thereof, or a combination thereof.
    Type: Application
    Filed: August 15, 2016
    Publication date: January 3, 2019
    Inventors: Alana Lea GRAY, James CARDELLI, David Thomas COLEMAN, Khalid EL-SAYED, Mohamed M. MOHYELDIN