Patents by Inventor Alana M. O'Reilly

Alana M. O'Reilly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies To Cell Adhesion Molecule-Related/Down-Regulated By Oncogenes (CDON) And Uses Thereof
    Publication number: 20220289840
    Abstract: The present disclosure provides antibodies specifically binding N-terminal or C-terminal regions of Cell Adhesion Molecule-Related/Down-Regulated By Oncogenes (CDON) polypeptide, methods of making the same, and methods of treating humans having tumors by administering the antibody.
    Type: Application
    Filed: February 12, 2020
    Publication date: September 15, 2022
    Inventors: Denise C. Connolly, Alana M. O'Reilly, Tiffiney R. Hartman, Valerie L. Sodi
  • Activated mutants of SH2-domain-containing protein tyrosine phosphatases and methods of use thereof
    Patent number: 6156551
    Abstract: The invention relates to novel mutant SH2 domain containing protein tyrosine phosphatases wherein the phosphatase is partially or constitutively active; and whose ability to regulate biological processes are different from the wildtype protein tyrosine phosphatases. The invention also relates to methods of use of the novel mutants, for example, in in vitro assays to screen for binding partners and inhibitors of protein tyrosine phosphatases and in the treatment of protein tyrosine phosphatase mediated diseases or conditions.
    Type: Grant
    Filed: June 5, 1998
    Date of Patent: December 5, 2000
    Assignees: Beth Israel Deaconess Medical Center, Joslin Diabetes Center
    Inventors: Benjamin G. Neel, Alana M. O'Reilly, Steven Shoelson, Scott Pluskey