Patents by Inventor Alangar Sathyaranjandas Hedge

Alangar Sathyaranjandas Hedge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8883419
    Abstract: The present invention relates to novel primers for identification of astrocytoma, it's grades and glioblastoma prognosis. Further, disclosed is a method of diagnosing the presence of different grades of diffuse astrocytoma and glioblastoma, in a human subject, which involves detection of the expression levels of said genes in tumor tissue samples in comparison to normal brain. Also disclosed is a method of distinguishing between the two types of Glioblastoma—the progressive and de novo types. Also disclosed is a method of prognosis of glioblastoma based on the expression of the gene PBEF1, wherein the higher level of expression of the gene in the tumor sample, indicates poorer survival of the human subject. The disclosed compositions are useful, for example, in the diagnosis, prevention, treatment and/or prognosis of astrocytoma. The invention further provides kits for the detection and prognosis of the said diseases.
    Type: Grant
    Filed: January 6, 2009
    Date of Patent: November 11, 2014
    Assignee: Council of Scientific & Industrial Research
    Inventors: Kumaravel Somasundaram, Paturu Kondaiah, Vani Santosh, Anandh Balasubramaniam, Alangar Sathyaranjandas Hedge, Ashwathnarayana Rao Chandramouli, Manchanahalli Rangaswamy Sathyanarayana Rao
  • Publication number: 20110027784
    Abstract: The present invention relates to novel primers for identification of astrocytoma, it's grades and glioblastoma prognosis. Further, disclosed is a method of diagnosing the presence of different grades of diffuse astrocytoma and glioblastoma, in a human subject, which involves detection of the expression levels of said genes in tumor tissue samples in comparison to normal brain. Also disclosed is a method of distinguishing between the two types of Glioblastoma—the progressive and de novo types. Also disclosed is a method of prognosis of glioblastoma based on the expression of the gene PBEF1, wherein the higher level of expression of the gene in the tumor sample, indicates poorer survival of the human subject. The disclosed compositions are useful, for example, in the diagnosis, prevention, treatment and/or prognosis of astrocytoma. The invention further provides kits for the detection and prognosis of the said diseases.
    Type: Application
    Filed: January 6, 2009
    Publication date: February 3, 2011
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Kumaravel Somasundaram, Paturu Kondaiah, Vani Santosh, Anandh Balasubramaniam, Alangar Sathyaranjandas Hedge, Ashwathnarayana Rao Chandramouli, Manchanahalli Rangaswamy Sathyanarayana Rao