Patents by Inventor Alasdair MacLean

Alasdair MacLean has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF NON-NEURONAL CANCER USING HSV-1 VARIANTS
    Publication number: 20070292394
    Abstract: A mutant herpes simplex virus which has been modified in the ?34.5 gene such that the gene is non-functional is used to treat a non-neuronal cancer such as a mesothelioma, ovarian carcinoma, bladder cancer or melanoma. Typically, the mutant herpes simplex virus has been modified within the BamHI restriction fragment of the long terminal repeat of the viral genome.
    Type: Application
    Filed: June 19, 2007
    Publication date: December 20, 2007
    Inventors: Susanne Brown, Alasdair Maclean, Nigel Fraser, Bruce Randazzo, Steven Albelda, Larry Kaiser, John Kucharczuk
  • Treatment of cancer using HSV mutant
    Publication number: 20050260169
    Abstract: Use as an anti-cancer agent of a mutant herpes simplex virus wherein the mutant virus comprises a modification in the ?34.5 gene in the long repeat region (RL) such that the ?34.5 gene is a non-functional, manufacture of medicaments and methods of testing cancer in mammals employing HSV mutant.
    Type: Application
    Filed: June 13, 2005
    Publication date: November 24, 2005
    Inventors: Alasdair MacLean, Susanne Brown, Nigel Fraser, Bruce Randazzo
  • Treatment of non-neuronal cancer using HSV-1 variants
    Publication number: 20050226850
    Abstract: A mutant herpes simplex virus which has been modified in the ?34.5 gene such that the gene is non-functional is used to treat a non-neuronal cancer such as a mesothelioma, ovarian carcinoma, bladder cancer or melanoma. Typically, the mutant herpes simplex virus has been modified within the BamHI restriction fragment of the long terminal repeat of the viral genome.
    Type: Application
    Filed: June 8, 2005
    Publication date: October 13, 2005
    Inventors: Susanne Brown, Alasdair MacLean, Nigel Fraser, Bruce Randazzo, Steven Albelda, Larry Kaiser, John Kucharczuk