Abstract: A medicament delivery device including a housing for receiving a syringe, the housing having first and second casing parts separably attachable to one another. The device further includes a sleeve receivable within the housing and including a tubular wall having an inner surface delimiting a bore and an opposing outer surface. A locking member is receivable within the second casing part such that the locking member is axially movable between first and second axial positions relative to the second casing part. In the first axial position the locking member is engageable with the outer surface to inhibit an axial movement of the sleeve relative to the first casing part. In the second axial position the locking member is disengageable from the outer surface. The device, in one or more embodiments, includes an application as an autoinjector.

Abstract: A medicament delivery device comprises a housing and a syringe axially movable in the housing and the syringe having a barrel. The device further comprises a stopper axially movable in the barrel and which separates a first chamber and second chamber from one another. The stopper is axially movable in the barrel in response to a vapour pressure being received in the second chamber. The device also includes a biasing mechanism to axially move the syringe in the housing between a first syringe position and a second syringe position in response to a first reduction in the vapour pressure in the second chamber. In the first syringe position venting of the propellant from the second chamber through a first fluid pathway is permitted to enable the first reduction in the vapour pressure in the second chamber while venting of the propellant from the second chamber through a second fluid pathway is substantially prevented.

Abstract: A medicament delivery device including a housing for receiving a syringe, the housing having first and second casing parts separably attachable to one another. The device further includes a sleeve receivable within the housing and including a tubular wall having an inner surface delimiting a bore and an opposing outer surface. A locking member is receivable within the second casing part such that the locking member is axially movable between first and second axial positions relative to the second casing part. In the first axial position the locking member is engageable with the outer surface to inhibit an axial movement of the sleeve relative to the first casing part. In the second axial position the locking member is disengageable from the outer surface. The device, in one or more embodiments, includes an application as an autoinjector.

Abstract: A sub-assembly of a medicament delivery device, the sub-assembly including a housing for containing a propellant source, and a locking ring for attachment to the housing. The housing is configured to receive a flange of a syringe, the locking ring is configured to retain a syringe flange received in the housing between the locking ring and the housing when the locking ring is attached to the housing.

Abstract: A medicament delivery device (10) comprising a syringe (12) having a barrel with an open end, and an axially moveable stopper (18) received in the barrel separating a first chamber axially forwards of the stopper from a second chamber axially rearwards of the stopper. The medicament delivery device further including an expandable drive housing (24) arranged to receive a propellant from a propellant source (36) for providing a vapour pressure, the expandable drive housing having a narrow channel in fluid communication with the second chamber. The expandable drive housing is expandable upon receiving propellant from the propellant source and, upon expansion, causes forward axial movement of the syringe.

Abstract: A medicament delivery device has a syringe, a housing, a needle shield, a biasing member and one or more blocking members. The needle shield is biased axially forwardly by the biasing member so as to selectively cover a needle of the syringe. However, the biasing member is prevented from biasing the needle shield axially forwardly until a radial movement of the blocking members has occurred, which is precipitated by a forward axial movement of the syringe. Consequently, the forward movement of the syringe releases the needle shield to automatically make safe the device.

Abstract: A medicament delivery device including a first container having a delivery outlet at a front end thereof and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container, where the first chamber is axially forwards of the first stopper and the second chamber is axially rearwards of the first stopper. The medicament delivery device further includes a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, where the third chamber is axially forwards of the second stopper and the fourth chamber is axially rearwards of the second stopper, and where the third chamber has a vent outlet in fluid communication with a venting chamber.

Abstract: An injection device having an outer housing configured to receive a syringe. The syringe has a barrel for containing medicament and a needle in fluid communication with the barrel. The device further has a needle shield axially moveable relative to the outer housing between a needle covering position and a needle exposing position and a helical compression spring to bias the needle shield axially forwardly toward the needle covering position. A locking sleeve, axially movable relative to the outer housing between a non-locking position and a locking position, selectively limits axial movement of the needle shield. In a first configuration, the needle shield is axially slideable within the locking sleeve to permit rearward axial movement of the needle shield from the needle covering position to the needle exposing position.

Abstract: A medicament delivery device comprises a housing and a syringe axially movable in the housing and the syringe having a barrel. The device further comprises a stopper axially movable in the barrel and which separates a first chamber and second chamber from one another. The stopper is axially movable in the barrel in response to a vapour pressure being received in the second chamber. The device also includes a biasing mechanism to axially move the syringe in the housing between a first syringe position and a second syringe position in response to a first reduction in the vapour pressure in the second chamber. In the first syringe position venting of the propellant from the second chamber through a first fluid pathway is permitted to enable the first reduction in the vapour pressure in the second chamber while venting of the propellant from the second chamber through a second fluid pathway is substantially prevented.

Abstract: A sub-assembly for a medicament delivery device including a housing, a propellant source contained in and axially moveable relative to said housing, and a button axially moveable relative to said housing. At least part of said button is disposed axially rearwardly of part of said propellant source. The button includes one or more radially flexible blocking members, and the button is moveable between a first axial position in which the one or more radially flexible blocking members are radially restrained by the housing in a radially inward position that limits rearward axial movement of the propellant source, and a second axial position in which the one or more radially flexible blocking members are able to flex to a radially outward position and permit rearward axial movement of the propellant source relative to the button and the housing.

Abstract: An injection device having an outer housing configured to receive a syringe. The syringe has a barrel for containing medicament and a needle in fluid communication with the barrel. The device further has a needle shield axially moveable relative to the outer housing between a needle covering position and a needle exposing position and a biasing means to bias the needle shield axially forwardly toward the needle covering position. A locking sleeve, axially movable relative to the outer housing between a non-locking position and a locking position, selectively limits axial movement of the needle shield. In a first configuration, the needle shield is axially slideable within the locking sleeve to permit rearward axial movement of the needle shield from the needle covering position to the needle exposing position.

Abstract: A sub-assembly of a medicament delivery device, the sub-assembly including a propellant source having a reservoir housing defining a reservoir and a stem having a bore therethrough, at least one inlet in fluid communication with the bore, and an open outlet end in fluid communication with the bore, the stein being moveable relative to the reservoir housing between a first position in which the at least one inlet is not in fluid communication with the reservoir and a second position in which the at least one inlet is in fluid communication with the reservoir, the propellant source further including a biasing member for biasing the stem towards the first position. The sub-assembly further including a collet member having a first plurality of radially flexible fingers and a second plurality of radially flexible fingers.

Abstract: A medicament delivery device has a syringe, a housing, a needle shield, a biasing member and one or more blocking members. The needle shield is biased axially forwardly by the biasing member so as to selectively cover a needle of the syringe. However, the biasing member is prevented from biasing the needle shield axially forwardly until a radial movement of the blocking members has occurred, which is precipitated by a forward axial movement of the syringe. Consequently, the forward movement of the syringe releases the needle shield to automatically make safe the device.

Abstract: A medicament delivery device (10) comprising a syringe (12) having a barrel with an open end, and an axially moveable stopper (18) received in the barrel separating a first chamber axially forwards of the stopper from a second chamber axially rearwards of the stopper. The medicament delivery device further including an expandable drive housing (24) arranged to receive a propellant from a propellant source (36) for providing a vapour pressure, the expandable drive housing having a narrow channel in fluid communication with the second chamber. The expandable drive housing is expandable upon receiving propellant from the propellant source and, upon expansion, causes forward axial movement of the syringe.

Abstract: A valve for discharging a fluid, comprising: a valve body at least partially defining a fluid chamber; and a valve stem extending into the fluid chamber, the valve stem comprising an outlet port for transfer, in use, of fluid from the fluid chamber into the valve stem; the valve stem being slidably movable relative to the valve body from: i) a non-dispensing position in which the outlet port is out of communication with the fluid chamber; to ii) a dispensing position in which the outlet port is in fluid communication with the fluid chamber so as to permit transfer of the fluid from the fluid chamber into the valve stem; wherein the valve further comprises a locking member which is configured to prevent return of the valve stem into the non-dispensing position once the valve stem slides beyond a locking position.

Abstract: A sub-assembly of a medicament delivery device, the sub-assembly including a housing for containing a propellant source, and a locking ring for attachment to the housing. The housing is configured to receive a flange of a syringe, the locking ring is configured to retain a syringe flange received in the housing between the locking ring and the housing when the locking ring is attached to the housing.

Abstract: A sub-assembly of a medicament delivery device, the sub-assembly comprising including a propellant source having a reservoir housing defining a reservoir and a stem having a bore therethrough, at least one inlet in fluid communication with the bore, and an open outlet end in fluid communication with the bore, the stein being moveable relative to the reservoir housing between a first position in which the at least one inlet is not in fluid communication with the reservoir and a second position in which the at least one inlet is in fluid communication with the reservoir, the propellant source further including a biasing member for biasing the stem towards the first position. The sub-assembly further including a collet member having a first plurality of radially flexible fingers and a second plurality of radially flexible fingers.

Abstract: A medicament delivery device comprising a first container having a delivery outlet at a front end thereof and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container, where the first chamber is axially forwards of the first stopper and the second chamber is axially rearwards of the first stopper. The medicament delivery device further comprising a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, where the third chamber is axially forwards of the second stopper and the fourth chamber is axially rearwards of the second stopper, and where the third chamber has a vent outlet in fluid communication with a venting chamber.

Abstract: A sub-assembly of a medicament delivery device including a propellant source having a reservoir for containing a propellant and a stem for dispensing propellant from the reservoir, the stem extending axially along a longitudinal axis and having an open outlet end and a bore therethrough that is in fluid communication with the open outlet end and is selectively in fluid communication with the reservoir. The sub-assembly also includes a spray head member attachable to the stem. The spray head member is arranged to radially deflect propellent passing through the bore of the stem relative to the longitudinal axis.

Abstract: A sub-assembly for a medicament delivery device including a housing, a propellant source contained in and axially moveable relative to said housing, and a button axially moveable relative to said housing. At least part of said button is disposed axially rearwardly of part of said propellant source. The button includes one or more radially flexible blocking members, and the button is moveable between a first axial position in which the one or more radially flexible blocking members are radially restrained by the housing in a radially inward position that limits rearward axial movement of the propellant source, and a second axial position in which the one or more radially flexible blocking members are able to flex to a radially outward position and permit rearward axial movement of the propellant source relative to the button and the housing.