Patents by Inventor Alban J. Linnenbach

Alban J. Linnenbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Soluble variants of type I membrane proteins, and methods of using them
    Patent number: 6645498
    Abstract: The present invention describes novel soluble variants of type I membrane protein GA733-2 and methods of making and using them. In addition, the present invention describes a method of converting type I membrane proteins into secretory proteins which may be used for active immunotherapy against carcinomas and as reagents in the detection of GA733-2 expression on tumor cells.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: November 11, 2003
    Assignee: The Wistar Institute of Anatomy and Biology
    Inventors: Alban J. Linnenbach, Hilary Koprowski, Dorothee Herlyn
  • Soluble variants of type I membrane proteins, and methods of using them
    Publication number: 20030103935
    Abstract: The present invention describes novel soluble variants of type I membrane protein GA733-2 and methods of making and using them. In addition, the present invention describes a method of converting type I membrane proteins into secretory proteins which may be used for active immunotherapy against carcinomas and as reagents in the detection of GA733-2 expression on tumor cells.
    Type: Application
    Filed: November 19, 2002
    Publication date: June 5, 2003
    Applicant: The Wistar Institute of Anatomy and Biology
    Inventors: Alban J. Linnenbach, Hilary Koprowski, Dorothee Herlyn
  • DNA and polypeptide for tumor-associated antigen CO-029
    Patent number: 5668002
    Abstract: The human tumor-associated antigen CO-029 is a monoclonal antibody-defined, 27-34 kDa cell surface glycoprotein. A full-length cDNA clone for CO-029 is described. When transiently expressed in COS cells, the cDNA clone directs the synthesis of an antigen reactive with monoclonal antibody CO-029 in mixed hemadsorption and immunoblot assays. Sequence analysis reveals that CO-029 belongs to a family of cell surface antigens which includes the melanoma-associated antigen ME491, the leukocyte cell surface antigen CD37, and the Sm23 antigen of the parasitic helminth Schistosoma mansoni.
    Type: Grant
    Filed: August 31, 1990
    Date of Patent: September 16, 1997
    Assignee: The Wistar Institute
    Inventors: Alban J. Linnenbach, Hilary Koprowski, Stanislaw Szala