Abstract: An extraction vial includes a reservoir portion having generally parallel walls, a neck portion defining an opening into the reservoir portion and a channel surrounding the opening, a nozzle portion integral with reservoir portion at a second end of the reservoir, a sealing closure that closes the nozzle, a base integral with the sealing closure and including a support surface adapted to support the vial in an upright position, and a cap received and removably maintained within the channel. An extraction liquid may be contained within the vial for extracting sample from a carrier. The vial may be used by adding the carrier to the extraction liquid within the vial, closing the vial with the cap, agitating the vial to release sample from the carrier, and removing at least the sealing closure or, preferably, the sealing closure and base whereby extraction liquid can be expelled from the vial.