Patents by Inventor Albert H. M. Th. Van Heertum

Albert H. M. Th. Van Heertum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Piperazine derivatives
    Patent number: 4377578
    Abstract: Novel 1-substituted 4-(diarylmethyl)piperazine derivatives having antianaphylactic and antihistaminic properties.
    Type: Grant
    Filed: July 24, 1981
    Date of Patent: March 22, 1983
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Jan Vandenberk, Ludo E. J. Kennis, Marcel J. M. C. Van der Aa, Albert H. M. Th. Van Heertum
  • 1,3-Dihydro-1-[(1-piperidinyl)alkyl]-2H-benzimidazol-2-one derivatives
    Patent number: 4254127
    Abstract: Novel 1,3-dihydro-1-[(1-piperidinyl)alkyl]-2H-benzimidazol-2-one derivatives which compounds are potent serotonin-antagonists and central nervous system depressants, having utility as antiemetic, neuroleptic and anti-congestive agents.
    Type: Grant
    Filed: April 3, 1980
    Date of Patent: March 3, 1981
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Jan Vandenberk, Ludo E. J. Kennis, Albert H. M. Th. Van Heertum, Marcel J. M. C. Van der Aa
  • 1-[(Heterocyclyl)-alkyl]-4-diarylmethoxy piperidine derivatives
    Patent number: 4200641
    Abstract: Novel 1-[(heterocyclyl)alkyl]-4-diarylmethoxy piperidine derivatives are disclosed having the formula ##STR1## where n is 2-6, Ar.sup.1 and Ar.sup.2 are aryl and B is a substituted benzimidazolyl radical. These compounds are useful for their antianaphylactic and antihistaminic properties. Specific claimed compounds are 1-{3-[4-(diphenylmethoxy)-1-piperidinyl]-propyl}-1,3-dihydro-2H-benzimidaz ol-2-one, 1-{2-[4-(diphenylmethoxy)-1-piperidinyl]ethyl}1-, 3-dihydro-2H-benzimidazol-2-one, and 1-{4-[4-(diphenylmethoxy)-1-piperidinyl]butyl}-1,3-dihydro-2H-benzimidazol -2-one.
    Type: Grant
    Filed: February 6, 1978
    Date of Patent: April 29, 1980
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Jan Vandenberk, Ludo E. J. Kennis, Marcel J. M. C. Van der Aa, Albert H. M. Th. Van Heertum
  • Antiemetic 1-(benzoxazolylalkyl)-piperidine derivatives
    Patent number: 4175129
    Abstract: Compounds of the class of 1-(benzazolylalkyl)piperidine derivatives useful as antiemetic agents.
    Type: Grant
    Filed: July 20, 1977
    Date of Patent: November 20, 1979
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Jan Vandenberk, Ludo E. J. Kennis, Marcel J. M. C. Van der Aa, Albert H. M. Th. Van Heertum
  • Antiemetic 1-(benzothiazolylalkyl)piperidine derivatives
    Patent number: 4160836
    Abstract: Compounds of the class of 1-(benzazolylalkyl)piperidine derivatives useful as antiemetic agents.
    Type: Grant
    Filed: July 20, 1977
    Date of Patent: July 10, 1979
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Jan Vandenberk, Ludo E. J. Kennis, Marcel J. M. C. Van Der Aa, Albert H. M. Th. Van Heertum
  • Antiemetic, 1-(benzimidazolyl-alkyl)-piperidine derivatives
    Patent number: 4126687
    Abstract: Compounds of the class of 1-(benzazolylalkyl)piperidine derivatives useful as antiemetic agents.
    Type: Grant
    Filed: July 20, 1977
    Date of Patent: November 21, 1978
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Jan Vandenberk, Ludo E. J. Kennis, Marcel J. M. C. Van der Aa, Albert H. M. Th. Van Heertum
  • Antiemetic 1-(benzotriazolyl-alkyl)-piperidine derivatives
    Patent number: 4126688
    Abstract: Compounds of the class of 1-(benzazolylalkyl)piperidine derivatives useful as antiemetic agents.
    Type: Grant
    Filed: July 20, 1977
    Date of Patent: November 21, 1978
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Jan Vandenberk, Ludo E. J. Kennis, Marcel J. M. C. Van der Aa, Albert H. M. Th. Van Heertum
  • 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds
    Patent number: 4110333
    Abstract: Chemical compounds of the formula ##STR1## wherein B, R.sup.1, R.sup.2, R.sup.3, R.sup.7, R.sup.8, m and n are as defined hereinbelow, which compounds are intermediates for the preparation of antiemetic agents.
    Type: Grant
    Filed: July 20, 1977
    Date of Patent: August 29, 1978
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Jan Vandenberk, Ludo E. J. Kennis, Marcel J. M. C. Van der Aa, Albert H. M. Th. Van Heertum
  • 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds
    Patent number: 4066772
    Abstract: Compounds of the class of 1-(benzazolyalkyl)piperidine derivatives useful as antiemetic agents.
    Type: Grant
    Filed: May 17, 1976
    Date of Patent: January 3, 1978
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Jan Vandenberk, Ludo E. J. Kennis, Marcel J. M. C. Van der Aa, Albert H. M. Th. Van Heertum
  • 1-Benzazolylalkyl-4-substituted-piperidines
    Patent number: 4035369
    Abstract: Compounds of the class of 1-(benzazolyalkyl)piperidine derivatives, useful as neuroleptic agents.
    Type: Grant
    Filed: August 10, 1976
    Date of Patent: July 12, 1977
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Jan Vandenberk, Ludo E. J. Kennis, Marcel J. M. C. Van der Aa, Albert H. M. Th. Van Heertum
  • Benzimidazolinone derivatives
    Patent number: 3989707
    Abstract: Novel benzimidazolinone derivatives and therapeutically acceptable acid addition salts thereof, said compounds being useful as long acting neuroleptic agents.
    Type: Grant
    Filed: June 21, 1974
    Date of Patent: November 2, 1976
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Paul Adriaan Jan Janssen, Albert H. M. Th. Van Heertum, Jan Vandenberk, Marcel J. M. C. Van der Aa