Abstract: Disclosed are methods and systems for solid phase transfer of a reagent to a substrate. In some embodiments, the method comprises providing at least a first composition comprising a solid phase, wherein the solid phase comprises a reagent; and dispensing a first sample from the first composition onto a first coordinate on a substrate, whereby the first reagent is transferred to the substrate from the solid phase.

Abstract: An embodiment in accordance with the present invention provides a synthetic lens capsule for use in IOL fixation that is compatible with current and future IOL implants and relatively straightforward to implant. The device of the present invention can be inserted into the eye via a small (<3.0 mm) incision in the eye wall. The device of the present invention is compatible with all known or conceivable ways of securing the device to the eye. Securement is preferably done with at least two-point securement. In some embodiments, the device may also include a proprietary or conventional method of securement. To allow for expansion of the device as space permits, the device can also include a flexible ring structure. The device can include at least one aperture for the passage of light. The device of the present invention simplifies visual rehabilitation in cases of inadequate capsular support for IOL fixation.

Abstract: Processes and systems for non-destructively storing, accessing, and editing information using nucleic acids are disclosed. Representative processes include a process for extracting a data file from a database, wherein the data file comprises information encoded into one or more polynucleotide strands and wherein the database comprises a plurality of polynucleotide strands; a process for expanding a number of unique data files in a database that can be addressed with a predetermined number of oligonucleotide primers, wherein the unique data files each comprise information encoded into one or more polynucleotide strands and wherein the database comprises a plurality of polynucleotide strands; a process for differentially reading information encoded into one or more polynucleotide strands; a process for manipulating files while in storage; and a process for extracting a data file from a database, wherein the data file comprises information encoded into a polynucleotide strand.

Abstract: An embodiment in accordance with the present invention provides a synthetic lens capsule for use in IOL fixation that is compatible with current and future IOL implants and relatively straightforward to implant. The device of the present invention can be inserted into the eye via a small (<3.0 mm) incision in the eye wall. The device of the present invention is compatible with all known or conceivable ways of securing the device to the eye. Securement is preferably done with at least two-point securement. In some embodiments, the device may also include a proprietary or conventional method of securement. To allow for expansion of the device as space permits, the device can also include a flexible ring structure. The device can include at least one aperture for the passage of light. The device of the present invention simplifies visual rehabilitation in cases of inadequate capsular support for IOL fixation.

Abstract: A surgical tool assembly is disclosed. The surgical tool assembly includes a forceps instrument including a proximal handle portion with an actuator, and a distal forceps portion including jaws. The actuator selectively moves the jaws. The surgical tool assembly includes an infusion assembly including a tube configured to be connected to a fluid source at a primary tube end and connected to a fitting at a paracentesis tube end. The fitting defines a passage configured to receive the distal forceps portion of the forceps instrument. An infusion sleeve extends away from the fitting. The infusion sleeve is arranged concentric around an outer surface of the distal forceps portion to define a fluid pathway. The jaws extend beyond a terminal end of the infusion sleeve such that the jaws are arranged outside of the infusion sleeve.