Patents by Inventor Albert Khilevich

Albert Khilevich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BTK inhibitor compounds
    Patent number: 11542249
    Abstract: The invention provides BTK Inhibitor compounds of the formula pharmaceutically acceptable salts, pharmaceutical compositions thereof, and methods of using these compounds, salts, or compositions to treat autoimmune diseases such as Rheumatoid Arthritis.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: January 3, 2023
    Assignee: Eli Lilly and Company
    Inventors: Kenneth James Henry, Jr., Albert Khilevich, Steven Lee Kuklish, Katherine Marie Partridge, Steven James Quimby
  • BTK INHIBITOR COMPOUNDS
    Publication number: 20200290997
    Abstract: The invention provides BTK Inhibitor compounds, pharmaceutically acceptable salts, pharmaceutical compositions thereof, and methods of using these compounds, salts, or compositions to treat autoimmune diseases such as Rheumatoid Arthritis.
    Type: Application
    Filed: October 30, 2018
    Publication date: September 17, 2020
    Inventors: Kenneth James Henry, Jr., Albert Khilevich, Steven Lee Kuklish, Katherine Marie Partridge, Steven James Quimby
  • 6-substituted-3-1,3-benzothiazol-2-one compounds as TARP-gamma 8 dependent AMPA receptor antagonists
    Patent number: 9469632
    Abstract: A TARP ?8 dependant AMPA receptor antagonist of the formula: wherein X is CH or N; A is and R1 is as defined herein; its pharmaceutically acceptable salts, uses, and methods for its preparation are described.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: October 18, 2016
    Assignee: Eli Lilly and Company
    Inventors: Kevin Matthew Gardinier, Douglas Linn Gernert, Patric James Hahn, Sean Patrick Hollinshead, Albert Khilevich, Daniel Ray Mayhugh, Paul Leslie Ornstein, Warren Jaye Porter, Jon Kevin Reel, Jeffrey Michael Schkeryantz, Patrick Gianpietro Spinazze, Freddie Craig Stevens, Jeffrey Michael Witkin
  • 6-SUBSTITUTED-3H-1,3-BENZOTHIAZOL-2-ONE COMPOUNDS AS TARP-GAMMA 8 DEPENDENT AMPA RECEPTOR ANTAGONISTS
    Publication number: 20150344468
    Abstract: A TARP ?8 dependant AMPA receptor antagonist of the formula: wherein X is CH or N; A is and R1 is as defined herein; its pharmaceutically acceptable salts, uses, and methods for its preparation are described.
    Type: Application
    Filed: May 21, 2015
    Publication date: December 3, 2015
    Inventors: Kevin Matthew GARDINIER, Douglas Linn GERNERT, Patric James HAHN, Sean Patrick HOLLINSHEAD, Albert KHILEVICH, Daniel Ray MAYHUGH, Paul Leslie ORNSTEIN, Warren Jaye PORTER, Jon Kevin REEL, Jeffrey Michael SCHKERYANTZ, Patrick Gianpietro SPINAZZE, Freddie Craig STEVENS, Jeffrey Michael WITKIN
  • Potentiators of glutamate receptors
    Patent number: 7858646
    Abstract: The present invention provides compounds of formula (I); pharmaceutical compositions thereof, and methods of using the same, processes or preparing the same, and intermediates thereof.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: December 28, 2010
    Assignee: Eli Lilly and Company
    Inventors: Thomas Daniel Aicher, Dana Rae Benesh, Maria-Jesus Blanco-Pillado, Guillermo S. Cortez, Todd Michael Groendyke, Albert Khilevich, James Allen Knobelsdorf, Fredrik Pehr Marmsäter, Jeffrey Michael Schkeryantz, Tony Pisal Tang
  • Potentiators of glutamate receptors
    Patent number: 7816523
    Abstract: This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application also relates to processes for preparing a compound of formula I, and intermediate compounds useful therein.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: October 19, 2010
    Assignee: Eli Lilly and Company
    Inventors: Thomas Daniel Aicher, Guillermo S. Cortez, Todd Michael Groendyke, Albert Khilevich, James Allen Knobelsdorf, Fredrik Pehr Marmsater, Jeffrey Michael Schkeryantz, Tony Pisal Tang
  • Potentiators of glutamate receptors
    Patent number: 7803938
    Abstract: This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application also relates to processes for preparing a compound of formula I, and intermediate compounds useful therein.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: September 28, 2010
    Assignee: Eli Lilly and Company
    Inventors: Thomas Daniel Aicher, Guillermo S. Cortez, Todd Micheal Groendyke, Albert Khilevich, James Allen Knobelsdorf, Fredrik Pehr Marmsater, Jeffrey Michael Schkeryantz, Tony Pisal Tang
  • Imidazole carboxamides
    Patent number: 7754742
    Abstract: The present invention provides certain imidazole carboxamide derivatives, pharmaceutical compositions thereof, methods of using the same and processes for preparing the same.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: July 13, 2010
    Assignee: Eli Lilly and Company
    Inventors: Albert Khilevich, Bin Liu, Daniel Ray Mayhugh, Jeffrey Michael Schkeryantz, Deyi Zhang
  • Potentiators of glutamate receptors
    Patent number: 7678794
    Abstract: The present invention provides a compound of formula (I): pharmaceutical compositions thereof, and methods of using the same, processes for preparing the same, and intermediates thereof.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: March 16, 2010
    Assignee: Eli Lilly and Company
    Inventors: Thomas Daniel Aicher, Guillermo S. Cortez, Todd Michael Groendyke, Albert Khilevich, James Allen Knobelsdorf, Fredrik Pehr Marmsater, Jeffrey Michael Schkeryantz, Tony Pisal Tang
  • IMIDAZOLE CARBOXAMIDES
    Publication number: 20100016373
    Abstract: The present invention provides certain imidazole carboxamide derivatives, pharmaceutical compositions thereof, methods of using the same and processes for preparing the same.
    Type: Application
    Filed: July 14, 2009
    Publication date: January 21, 2010
    Inventors: Albert Khilevich, Bin Liu, Daniel Ray Mayhugh, Jeffrey Michael Schkeryantz, Deyi Zhang
  • Potentiators Of Glutamate Receptors
    Publication number: 20090318483
    Abstract: This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application also relates to processes for preparing a compound of formula I, and intermediate compounds useful therein.
    Type: Application
    Filed: August 28, 2009
    Publication date: December 24, 2009
    Inventors: Thomas Daniel AICHER, Guillermo S. CORTEZ, Todd Micheal GROENDYKE, Albert KHILEVICH, James Allen KNOBELSDORF, Fredrik Pehr MARMSATER, Jeffrey Michael SCHKERYANTZ, Tony Pisal TANG
  • Potentiators Of Glutamate Receptors
    Publication number: 20090318481
    Abstract: This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application also relates to processes for preparing a compound of formula I, and intermediate compounds useful therein.
    Type: Application
    Filed: August 28, 2009
    Publication date: December 24, 2009
    Inventors: Thomas Daniel AICHER, Guillermo S. CORTEZ, Todd Michael GROENDYKE, Albert KHILEVICH, James Allen KNOBELSDORF, Fredrik Pehr MARMSATER, Jeffrey Michael SCHKERYANTZ, Tony Pisal TANG
  • Potentiators of glutamate receptors
    Patent number: 7598423
    Abstract: This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application also relates to processes for preparing a compound of formula I, and intermediate compounds useful therein.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: October 6, 2009
    Assignee: Eli Lilly and Company
    Inventors: Thomas Daniel Aicher, Guillermo S. Cortez, Todd Michael Groendyke, Albert Khilevich, James Allen Knobelsdorf, Fredrik Pehr Marmsater, Jeffrey Michael Schkeryantz, Tony Pisal Tang, Nicholas Andrew Magnus
  • Potentiators Of Glutamate Receptors
    Publication number: 20080139505
    Abstract: The present invention provides compounds of formula (I): pharmaceutical compositions thereof, and methods of using the same, processes or preparing the same, and intermediates thereof.
    Type: Application
    Filed: November 15, 2005
    Publication date: June 12, 2008
    Inventors: Thomas Daniel Aicher, Guillermo S. Cortez, Todd Michael Groendyke, Albert Khilevich, James Allen Knobelsdorf, Fredrik Pehr Marmsater, Jeffrey Michael Schkeryantz, Tony Pisal Tang, Nicholas Andrew Magnus
  • Potentiators Of Glutamate Receptors
    Publication number: 20080096930
    Abstract: The present invention provides compounds of formula (I); pharmaceutical compositions thereof, and methods of using the same, processes or preparing the same, and intermediates thereof.
    Type: Application
    Filed: November 15, 2005
    Publication date: April 24, 2008
    Inventors: Thomas Aicher, Dana Benesh, Maria-Jesus Blanco-Pillado, Guillermo Cortez, Todd Groendyke, Albert Khilevich, James Knobelsdorf, Fredrik Marmsater, Jeffrey Schkeryantz, Tony Tang
  • Potentiators of Glutamate Receptors
    Publication number: 20080004321
    Abstract: The present invention provides a compound of formula (I): pharmaceutical compositions thereof, and methods of using the same, processes for preparing the same, and intermediates thereof.
    Type: Application
    Filed: November 15, 2005
    Publication date: January 3, 2008
    Inventors: Thomas Aicher, Guillermo Cortez, Todd Groendyke, Albert Khilevich, James Knobelsdorf, Fredrik Marmsater, Jeffrey Schkeryantz, Tony Tang
  • Heteroarylalkanoic acids as integrin receptor antagonists derivatives
    Publication number: 20050043344
    Abstract: The present invention relates to pharmaceutical compositions comprising compounds of the Formula I, or a pharmaceutically acceptable salt thereof, and methods of selectively inhibiting or antagonizing the ?V?3 and/or the ?V?5 integrin without significantly inhibiting the ?V?6 integrin.
    Type: Application
    Filed: December 22, 2003
    Publication date: February 24, 2005
    Inventors: Mark Boys, Lori Schretzman, Michael Tollefson, Nizal Chandrakumar, Ish Khanna, Maria Nguyen, Victoria Downs, Scott Mohler, Glen Gesicki, Thomas Penning, Barbara Chen, Yaping Wang, Albert Khilevich, Bipinchandra Desai, Yi Yu, John Wendt, Heather Stenmark, Hongwei Wu, Renee Huff, Srinivasan Nagarajan, Balekudru Devadas, Hwang-Fun Lu, Mark Russell, Dale Spangler, Mihir Parikh
  • Pyrazole compounds as integrin receptor antagonists derivatives
    Publication number: 20050004200
    Abstract: The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the ?V?3 and/or the ?V?5 integrin without significantly inhibiting the ?V?6 integrin.
    Type: Application
    Filed: December 19, 2003
    Publication date: January 6, 2005
    Inventors: Thomas Penning, Albert Khilevich, Barbara Chen, Preete Gandhi, Yaping Wang, Victoria Downs, Mark Boys, Mark Russell, Dale Spangler, Renee Huff
  • Gem-substituted alpha v beta 3 antagonists
    Publication number: 20040043994
    Abstract: The present invention relates to a class of compounds represented by the Formula I.
    Type: Application
    Filed: January 21, 2003
    Publication date: March 4, 2004
    Inventors: Ish Kumar Khanna, Yi Yu, Hwang-Fun Lu, Nizal S. Chandrakumar, Renee M. Huff, Mark Russell, Mark L. Boys, Lori A. Schretzman, Barbara B. Chen, Bipinchandra N. Desai, Srinivasan Raj Nagarajan, Alan F. Gasiecki, Thomas D. Penning, Thomas Rogers, John Adam Wendt, Albert Khilevich, Yaping Wang
  • 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use
    Publication number: 20030073850
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: February 17, 2000
    Publication date: April 17, 2003
    Inventors: Robert J. Altenbach, Michael D. Meyer, James F. Kerwin, Albert Khilevich, Teodozyj Kolasa, Jeffrey Rohde, William A. Carroll, Xenia Searle, Fan Yang