Patents by Inventor Albert Michiel van Rhee

Albert Michiel van Rhee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bis-benzimidazoles and related compounds as potassium channel modulators
    Patent number: 7482373
    Abstract: The present invention provides a genus of bis-benzimidazole compounds, methods and pharmaceutical compositions that are useful as modulators of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: January 27, 2009
    Assignee: Icagen, Inc.
    Inventors: Xiaodong Wang, Alan Bradley Fulp, Albert Michiel van Rhee, Kerry Leigh Spear
  • Method for producing chemical libraries enhanced with biologically active molecules
    Publication number: 20030120430
    Abstract: Methods and compositions for enhancing chemical libraries with biologically active molecules are taught. Relevant physicochemical descriptors that correlate with biological activity are calculated and selected. Database descriptors are identified using the physicochemical descriptors and an electronic database can be formed.
    Type: Application
    Filed: December 2, 2002
    Publication date: June 26, 2003
    Applicant: ICAgen, Inc.
    Inventor: Albert Michiel van Rhee
  • Method for screening compounds
    Publication number: 20020156586
    Abstract: A method for screening compounds for biological activity is disclosed. The method may include selecting a test set of compounds and selecting a training set of compounds. An assay is performed on the training set of compounds and training set data are formed. This data are entered into a digital computer, and an analytical model is formed. A subset of compounds is identified using the analytical model.
    Type: Application
    Filed: February 15, 2002
    Publication date: October 24, 2002
    Applicant: ICAgen, Inc.
    Inventors: Albert Michiel van Rhee, Kerry L. Spear, P. Kay Wagoner