Abstract: A patient positioning system configured for positioning and supporting a patient against movement on an operating table, the positioning system including a pair of arm positioners each configured to be positionable about an arm of the patient when the patient is lying on the operating table, each of the arm positioners provided as a sheet material configured to be wrapped around one of the arms of the patient to position each of the arm positioners to snugly envelope one of the arms and having releasable fasteners to maintain the arm positioners in the wrapped configuration; and an elongate lift sheet configured to extend across the operating table and underneath the back of the patient, the lift sheet being positioned to have opposite ends thereof wrapped over and around the arm protectors and tucked back under the lower back or sacrum of the patient to securely and snugly hold the lift sheet around the arm protectors and restrain the arms of the patient.