Patents by Inventor Albert S. Jones

Albert S. Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral compounds
    Patent number: 5585364
    Abstract: Compounds of formula I or a pharmaceutically acceptable salt thereof: ##STR1## in which formula R.sub.1 represents an aliphatic hydrocarbyl group; Ar represents a substituted or unsubstituted aromatic nucleus;X represents --SO.sub.2 -- or --CO-- andR.sub.2 and R.sub.3 which may be identical or different represent moieties of formula (a), (b), (c), (d), (e), (f), (g), (h) or (i): ##STR2## wherein B represents the residue of a nucleoside base of formula (A), (G), (C), (H) or (T): ##STR3## provided that when R.sub.2 and R.sub.3 both represent an unsubstituted moiety of formula (a) B represents the residue of a nucleoside base which is of formula (A), (G), (C) or (H) are of value for their antiviral activity.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 17, 1996
    Assignee: British Technology Group Limited
    Inventors: Richard T. Walker, Albert S. Jones
  • 2'Deoxy-5-(2-halogenovinyl)-uridines, pharmaceutical compositions and method of use
    Patent number: 4424211
    Abstract: The novel substance E-5-(2-bromovinyl)-2'-deoxyuridine and its corresponding iodovinyl derivative are gifted with specific antiviral activities towards herpes simplex virus. They may be synthesized by a condensation reaction followed by separation of anomers.
    Type: Grant
    Filed: December 21, 1981
    Date of Patent: January 3, 1984
    Assignees: Rega Instituut VZW, University of Birmingham
    Inventors: Albert S. Jones, Richard T. Walker, Erik D. A. de Clercq, Philip J. Barr
  • Antiviral agents, their preparation and use
    Patent number: 4383990
    Abstract: The compound of formula (I): ##STR1## wherein X is CFCl; and C.sub.1-6 alkanoyl esters and/or phosphate esters thereof, is active against herpes viruses.
    Type: Grant
    Filed: September 21, 1981
    Date of Patent: May 17, 1983
    Assignee: Beecham Group Limited
    Inventors: Paul L. Coe, Albert S. Jones, Stewart A. Noble, Richard T. Walker
  • E-5-(2-Halogenovinyl)-2'-deoxycytidines
    Patent number: 4382925
    Abstract: The invention relates to E-5-(2-halogenovinyl)-2'-deoxycytidines, e.g. E-5-(bromovinyl)-2'-deoxycytidine and E-5-(2-iodovinyl)-2'-deoxycytidine. These substances are endowed with specific antiviral activities towards herpes simplex virus and with an extremely low toxicity which makes them useful in antiviral medicines and for treatment of virus diseases in man and animal. They may be synthesized by introduction of an E-5-(2-halogenovinyl) sidechain into 2'-deoxycytidine, or by condensation of a trialkylsilyl derivative of E-5-(2-halogenovinyl)-cytosine with a hydroxyl-protected reactive derivative of 2'-deoxy-D-erythro-pentofuranose.
    Type: Grant
    Filed: October 2, 1980
    Date of Patent: May 10, 1983
    Assignees: The University of Birmingham, Stichting Rega V.Z.W.
    Inventors: Erik de Clercq, Gabriel A. Verhelst, Albert S. Jones, Richard T. Walker