Patents by Inventor Albert Tauler

Albert Tauler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein expression system
    Patent number: 9115364
    Abstract: The present invention relates to a method of producing a target protein, which method comprises expressing said protein in a host cell which contains a nucleic acid molecule which encodes a chimeric protein, said chimeric protein comprising a signal peptide from a non-mammalian bulk-secreted protein and said target protein; nucleic acids, vectors, host cells and kits for carrying out the method are also described.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: August 25, 2015
    Assignee: PROLUME LTD.
    Inventors: John Hesketh, Hanne Ravneberg, Christine Gjerdrum, Albert Tauler, Ian Pryme, Beate Stern
  • Protein Expression System
    Publication number: 20120142090
    Abstract: The present invention relates to a method of producing a target protein, which method comprises expressing said protein in a host cell which contains a nucleic acid molecule which encodes a chimeric protein, said chimeric protein comprising a signal peptide from a non-mammalian bulk-secreted protein and said target protein; nucleic acids, vectors, host cells and kits for carrying out the method are also described.
    Type: Application
    Filed: November 28, 2011
    Publication date: June 7, 2012
    Inventors: John Hesketh, Hanne Ravneberg, Christine Gjerdrum, Albert Tauler, Ian Pryme, Beate Stern
  • Protein expression system
    Patent number: 8067198
    Abstract: The present invention relates to a method of producing a target protein, which method comprises expressing said protein in a host cell which contains a nucleic acid molecule which encodes a chimeric protein, said chimeric protein comprising a signal peptide from a non-mammalian bulk-secreted protein and said target protein; nucleic acids, vectors, host cells and kits for carrying out the method are also described.
    Type: Grant
    Filed: June 25, 2004
    Date of Patent: November 29, 2011
    Assignee: Prolume Ltd.
    Inventors: John Hesketh, Hanne Ravneberg, Christine Gjerdrum, Albert Tauler, Ian Pryme, Beate Stern
  • Protein expression system
    Publication number: 20070142623
    Abstract: The present invention relates to a method of producing a target protein, which method comprises expressing said protein in a host cell which contains a nucleic acid molecule which encodes a chimeric protein, said chimeric protein comprising a signal peptide from a non-mammalian bulk-secreted protein and said target protein; nucleic acids, vectors, host cells and kits for carrying out the method are also described.
    Type: Application
    Filed: June 25, 2004
    Publication date: June 21, 2007
    Inventors: John Hesketh, Hanne Ravneberg, Christine Gjerdrum, Albert Tauler, Ian Pryne, Beate Stern
  • Expression system for the secretion of intracellular proteins
    Patent number: 6881832
    Abstract: Mammalian signal peptides can be used to aid in the secretion of mammalian proteins that are normally not secreted. By inactivating signals normally present in the 3? UTRs of mRNAs encoding proteins that are normally not secreted from mammalian cells, the proportion of such mRNA molecules directed to free and cytoskeletal bound polysomes can be reduced.
    Type: Grant
    Filed: March 2, 2000
    Date of Patent: April 19, 2005
    Assignee: UNI Targeting Research AS
    Inventors: John Edward Hesketh, Albert Tauler, Ian Fraser Pryme