Patents by Inventor Albert W. J. van Doorn

Albert W. J. van Doorn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for determining the presence or amount of analyte using a stable colloidal carbon sol
    Patent number: 5529901
    Abstract: This invention relates to a method for determining the presence or amount of an analyte in a sample comprising contacting the sample with a labeled constituent consisting of an aqueous carbon sol which is stable in the absence of a stabilizing substance. The colloidal carbon particles have directly conjugated to their surface a binding component which specifically binds to the analyte and the resulting analyte/carbon particle complex is used as an indication of the presence or amount of analyte in the sample. The grade of carbon used satisfies the condition V>0 wherein V is a linear predictor value according to the formula V=-138.954-0.987.times.DBP+15,609.times.VC+3.994.times.PPD, wherein DBP is the dibutylphthalate adsorption in ml/100 g, as determined according to DIN 53601; VC is the volatile content in %, as determined according to DIN 53552; and PPD is the average primary particle diameter in nanometers.
    Type: Grant
    Filed: May 12, 1994
    Date of Patent: June 25, 1996
    Assignee: Staat der Nederlanden
    Inventors: Albert W. J. Van Doorn, Jan H. Wichers, Wilhelmus M. J. Van Gelder
  • Method for an increased visualization of the reaction product of a specifically binding substance and a corresponding bindable substance and test kit therefor
    Patent number: 5348891
    Abstract: The invention herein is directed to a method for the visualization of the product of the reaction of a specifically binding substance and a corresponding bindable substance. The reaction product is formed during an assay procedure for the detection and/or determination of one of the components of the reaction. The assay involves the use of a component labeled by a sol of a non-metallic element, such as selenium and tellurium, and the use of a physical developer comprising a metal compound, such as silver lactate and silver nitrate, mercuric chloride and a copper sulfate, to strengthen or reinforce a specific signal, thereby improving detectability.
    Type: Grant
    Filed: June 12, 1992
    Date of Patent: September 20, 1994
    Assignee: H.B.T. Holland Biotechnology
    Inventors: Remco M. van Es, Gerrit D. Keizer, Albert W. J. van Doorn
  • Selenium or tellurium elemental hydrosols and their preparation
    Patent number: 5294370
    Abstract: The invention relates to a process for the preparation of a sol of a metallic or a non-metallic element, such as selenium, tellurium, gold and silver, wherein said process comprises the reduction of a chemical compound, which contains said element in a reducible state, with a borane compound, such as an alkali metal borohydride or an amine borane, as the reducing agent.
    Type: Grant
    Filed: February 19, 1992
    Date of Patent: March 15, 1994
    Assignees: HBT Holland Biotechnology B.V., Agrotechnologisch Onderzoekinstituut (ATO)
    Inventors: Jan H. Wickers, Wilhelmus M. J. van Gelder, Albert W. J. van Doorn