Abstract: A switchover manifold for selectively connecting one of a plurality of compressed gas vessels to a point of use such that the supply of compressed gas remains uninterrupted even as the compressed gas vessels are opened and closed to the point of use for renewal of depleted compressed gas vessels. The switchover manifold has an inlet for each gas vessel all in communication with a utilization outlet, and an externally operated valve which opens only one compressed gas vessel to the utilization outlet at any one time. The manifold may be utilized in conjunction with a gas bottle cart. The gas bottles may be medical side D bottles being used in association with a medical procedure comprising insufflation.