Abstract: A processing device receives a first cluster management operation request, wherein the first cluster management operation request is for a deployment operation of a first cluster and comprises a cluster template, a specified number of nodes to deploy and a configuration. The processing device determines a plurality of constraints from at least one of the cluster template or the configuration. The processing device deterministically solves for and outputs a first cluster layout comprising the specified number of nodes, each of the specified number of nodes comprising a hardware type, an image type and one or more services, wherein the first cluster layout satisfies the plurality of constraints.

Abstract: An incremental analog-to-digital converter (ADC) with high accuracy. The incremental ADC has a delta-sigma modulator, performing delta-sigma modulation on an analog input signal to output a quantized signal, and a digital filter, receiving the quantized signal to generate a digital representation of the analog input signal. A loop filter of the delta-sigma modulator has a preset circuit. In the preset circuit, the output terminal of the loop filter is preset rather than being reset during the reset phase of the incremental ADC.

Abstract: An incremental analog-to-digital converter (ADC) with high accuracy. The incremental ADC has a delta-sigma modulator, performing delta-sigma modulation on an analog input signal to output a quantized signal, and a digital filter, receiving the quantized signal to generate a digital representation of the analog input signal. A loop filter of the delta-sigma modulator has a preset circuit. In the preset circuit, the output terminal of the loop filter is preset rather than being reset during the reset phase of the incremental ADC.

Abstract: A processing device receives a first cluster management operation request, wherein the first cluster management operation request is for a deployment operation of a first cluster and comprises a cluster template, a specified number of nodes to deploy and a configuration. The processing device determines a plurality of constraints from at least one of the cluster template or the configuration. The processing device deterministically solves for and outputs a first cluster layout comprising the specified number of nodes, each of the specified number of nodes comprising a hardware type, an image type and one or more services, wherein the first cluster layout satisfies the plurality of constraints.

Abstract: A method for digital thermal monitoring assessment of vascular function comprising a temporary arterial occlusion using a pneumatic cuff positioned on a subject's upper limb, monitoring skin temperature at the fingertip of the occluded limb for a period of time before, during, and after the occlusion, calculating a Zero Reactivity Curve based on variables including start temperature, room temperature, and the slope of temperature decline during the occlusion, and assessing vascular function based on comparing the Zero Reactivity Curve and the observed temperature rebound after the occlusion is removed.

Abstract: A processing device receives a first cluster management operation request, wherein the first cluster management operation request is for a deployment operation of a first cluster and comprises a cluster template, a specified number of nodes to deploy and a configuration. The processing device determines a plurality of constraints from at least one of the cluster template or the configuration. The processing device deterministically solves for and outputs a first cluster layout comprising the specified number of nodes, each of the specified number of nodes comprising a hardware type, an image type and one or more services, wherein the first cluster layout satisfies the plurality of constraints.

Abstract: A processing device executing a provisioner requests a node level task from a server. The processing device receives an assignment of a first node level task, wherein the first node level task is associated with a cluster management operation for a first cluster. The processing device determines a first plugin capable of performing the first node level task from a plurality of plugins, wherein each of the plurality of plugins comprises a self-contained program for performing a specific set of node level tasks. The processing device performs the first node level task by the first plugin, wherein the first node level task is an operation on a remote target host that does not include software associated with the provisioner. The processing device reports a result of the node level task to the server.

Abstract: A multiple physiological signals sensing chip is provided. The multiple physiological signals sensing chip includes a substrate, a first light-emitting diode, a second light-emitting diode, a sensing array, and a processing unit. The substrate includes a contact surface touched by a finger. The first and second light-emitting diodes respectively emit red light and infrared light to the finger. The sensing array senses the red light or the infrared light reflected or refracted from the finger to obtain first physiological sensing signals according to a first sensing period or senses the red light and the infrared light reflected or refracted from the finger to obtain second physiological sensing signals according to a second sensing period. The first sensing period is shorter than the second sensing period. The processing unit respectively processes the first and second physiological sensing signals to obtain spatial information and energy information corresponding to the finger.

Abstract: A processing device receives a starting cluster layout for a first cluster, a target cluster layout for the first cluster, and a cluster management operation for creating or modifying the first cluster. The processing device determines a plurality of node level tasks to transition the first cluster from the starting cluster layout to the target cluster layout, determines dependencies between the plurality of node level tasks, and determines an order for the plurality of node level tasks based on the cluster management operation and the dependencies. The processing device then creates an execution plan that divides the cluster management operation into the plurality of node level tasks in the determined order.

Abstract: A method for digital thermal monitoring assessment of vascular function comprising a temporary arterial occlusion using a pneumatic cuff positioned on a subject's upper limb, monitoring skin temperature at the fingertip of the occluded limb for a period of time before, during, and after the occlusion, calculating a Zero Reactivity Curve based on variables including start temperature, room temperature, and the slope of temperature decline during the occlusion, and assessing vascular function based on comparing the Zero Reactivity Curve and the observed temperature rebound after the occlusion is removed.

Abstract: A method and system comprising image processing techniques that utilize spatio-spectral information relevant to an image, derived from multiple sets of selectively varied representations of the image to accurately and correctly identify illumination and material aspects of the image is provided. Blend pixels are detected to improve the accuracy of the identification of the illumination and material aspects of the image.

Abstract: A soft, weighted constraint imposed upon image locations temporally spaced in frames of a video, can be used to provide a more accurate segregation of an image into intrinsic material reflectance and illumination components. The constraint is arranged to constrain all color band variations between the image locations into one integral constraining relationship.

Abstract: A processing device receives a starting cluster layout for a first cluster, a target cluster layout for the first cluster, and a cluster management operation for creating or modifying the first cluster. The processing device determines a plurality of node level tasks to transition the first cluster from the starting cluster layout to the target cluster layout, determines dependencies between the plurality of node level tasks, and determines an order for the plurality of node level tasks based on the cluster management operation and the dependencies. The processing device then creates an execution plan that divides the cluster management operation into the plurality of node level tasks in the determined order.

Abstract: A processing device executing a provisioner requests a node level task from a server. The processing device receives an assignment of a first node level task, wherein the first node level task is associated with a cluster management operation for a first cluster. The processing device determines a first plugin capable of performing the first node level task from a plurality of plugins, wherein each of the plurality of plugins comprises a self-contained program for performing a specific set of node level tasks. The processing device performs the first node level task by the first plugin, wherein the first node level task is an operation on a remote target host that does not include software associated with the provisioner. The processing device reports a result of the node level task to the server.

Abstract: A processing device receives a first cluster management operation request, wherein the first cluster management operation request is for a deployment operation of a first cluster and comprises a cluster template, a specified number of nodes to deploy and a configuration. The processing device determines a plurality of constraints from at least one of the cluster template or the configuration. The processing device deterministically solves for and outputs a first cluster layout comprising the specified number of nodes, each of the specified number of nodes comprising a hardware type, an image type and one or more services, wherein the first cluster layout satisfies the plurality of constraints.

Abstract: A system and method for inducing physiological effects of ischemic conditioning and physiological effects of shear stress in a subject's body that mimic the effect of exercise on the subject. The disclosure includes a first device configured to cause ischemia, a second device configured to mechanically generate arterial shear stress, and a third device configured to monitor one or more of markers of ischemia or hemodynamic parameters and further including a microcontroller and actuators to cause the ischemia for a preset duration and then stop the ischemia for a preset duration, and to repeat the ischemia and reflow periods according to a preset program, simultaneously cause the second device to mechanically generate arterial shear stress according to a preset program of mechanical pulse amplitude, duration, and frequency; and to concurrently monitor hemodynamic parameters or markers of ischemia.

Abstract: A system and method for inducing physiological effects of ischemic conditioning and physiological effects of shear stress in a subject's body that mimic the effect of exercise on the subject. The disclosure includes a first device configured to cause ischemia, a second device configured to mechanically generate arterial shear stress, and a third device configured to monitor one or more of markers of ischemia or hemodynamic parameters and further including a microcontroller and actuators to cause the ischemia for a preset duration and then stop the ischemia for a preset duration, and to repeat the ischemia and reflow periods according to a preset program, simultaneously cause the second device to mechanically generate arterial shear stress according to a preset program of mechanical pulse amplitude, duration, and frequency; and to concurrently monitor hemodynamic parameters or markers of ischemia.

Abstract: Methods and a device for improving wound healing and for improving the effects of rehabilitative therapies in patients with cognitive and motor deficits are provided. Repeated regimens of remote ischemic conditioning are performed. Markers of ischemia are monitored in the tissue. The remote ischemic conditioning regimen may be adjusted based on the monitoring results. The remote ischemic conditioning regimen can be performed at a hospital, medical clinic, healthcare facility, or at a subject's home.

Abstract: The invention relates to an assay for discriminating between amyotrophic lateral sclerosis (ALS) patients and patients with ALS-like disorders that express symptoms like ALS. The method is based on the use of 2-dimensional (2D) gel electrophoresis to separate the complex mixture of proteins found in blood serum, the quantitation of a group of identified biomarkers, and the biostatistical analysis of the concentration of the identified biomarkers to differentiate patients having ALS from patients having other ALS-like disorders.

Abstract: Methods and apparatus for blood sampling from skin capillaries are provided. Blood extraction is improved by applying gradient pressure in a proximal to distal direction of an extremity. Blood is extracted and sampled from the skin capillaries with a blood sampling mechanism of at least a lancet and testing kit.