Patents by Inventor Alberto Ayala-Sarmiento

Alberto Ayala-Sarmiento has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR IN VIVO DUAL RECOMBINASE-MEDIATED CASSETTE EXCHANGE (dRMCE) AND DISEASE MODELS THEREOF
    Publication number: 20220304286
    Abstract: Described herein are donor vectors and systems for use in dual recombinase-mediated cassette exchange. Also described herein are animal models and human cells for consistent, rigorous, and facile investigation of transgene expression. Further described herein are methods of screening for therapeutic drugs using these animal models, and methods of treatment.
    Type: Application
    Filed: June 16, 2020
    Publication date: September 29, 2022
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Joshua Breunig, Moise Danielpour, Gi Bum Kim, Alberto Ayala-Sarmiento, Amy Yang