Abstract: A sole for footwear comprises an outer sole (12; 22; 31) housing a plurality of pressure-stimulation elements (15; 24; 33) movable perpendicularly, relative to the bearing surface of the outer sole, through the thickness of the outer sole and, in the absence of stresses, extending below the bearing surface of the outer sole by a predetermined distance in order, when the sole is pressed against a bearing surface, to exert, through a resilient intermediate element (17; 27; 35) comprising a soft inner sole of the footwear, a pressure localized at predetermined nerve centers in the sole of a foot on which the therapeutic footwear is worn.