Patents by Inventor Alberto J. Kaumann

Alberto J. Kaumann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Medicaments
    Patent number: 5637611
    Abstract: Use of a compound of general formula (I): ##STR1## wherein: R.sup.1 represents hydrogen, halogen, trifluoromethyl, nitro, hydroxy, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, arylC.sub.1-6 alkoxy, --CO.sub.2 R.sup.4, --(CH.sub.2).sub.n CN, --(CH.sub.2).sub.n CONR.sup.5 R.sup.6, --(CH.sub.2).sub.n SO.sub.2 NR.sup.5 R.sup.6, C.sub.1-6 alkanoylamino (CH.sub.2).sub.n, or C.sub.1-6 alkylsulphonylamino (CH.sub.2).sub.n ;R.sup.4 represents hydrogen, C.sub.1-6 alkyl or arylC.sub.1-6 alkyl;R.sup.5 and R.sup.6 each independently represent hydrogen or C.sub.1-6 alkyl, or R.sup.5 and R.sup.6 together with the nitrogen atom to which they are attached form a ring;n represents 0, 1 or 2; andR.sup.2 and R.sup.3 each independently represent hydrogen, C.sub.1-6 alkyl or benzyl or together with the nitrogen atom to which they are attached form a pyrrolidino, piperidino or hexahydroazepino ring;or a physiologically acceptable salt thereof, in the manufacture of a medicament for the treatment of a condition where a 5-HT.sub.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: June 10, 1997
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Francis D. King, Laramie M. Gaster, Alberto J. Kaumann, Rodney C. Young
  • Tryptamine analogues, their synthesis and their use as 5-HT.sub.1 -like or 5-HT.sub.2 receptor agonists
    Patent number: 5571833
    Abstract: The present invention relates to known and novel tryptamine analogues, processes and intermediates useful in their preparation, pharmaceutical compositions containing them and their use in therapy, in particular for the treatment and/or prophylaxis of disorders characterized by excessive vasodilatation, such as migraine and portal hypertension.
    Type: Grant
    Filed: May 26, 1994
    Date of Patent: November 5, 1996
    Assignee: SmithKline Beecham plc
    Inventors: Lawrence I. Kruse, Rodney C. Young, Alberto J. Kaumann
  • 5-HT.sub.4 receptor antagonists
    Patent number: 5492919
    Abstract: The invention provides the use of a compound of formula (I) ##STR1## wherein A, E, F, U, X, Y, Z, are as defined in the specification, or a pharmaceutically acceptable salt thereof, for the treatment of diarrhea predominant irritable bowel syndrome.
    Type: Grant
    Filed: July 6, 1994
    Date of Patent: February 20, 1996
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Gareth J. Sanger, Francis D. King, Gordon S. Baxter, Laramie M. Gaster, Alberto J. Kaumann, Guy A. Kennett, Keith R. Mulholland, Mythily Vimal, Kay A. Wardle, Paul A. Wyman, Rodney C. Young
  • Use of tetrahydrocarbazone derivatives as 5HT.sub.1 receptor agonists
    Patent number: 5464864
    Type: Grant
    Filed: December 23, 1993
    Date of Patent: November 7, 1995
    Assignee: SmithKline Beecham P.L.C.
    Inventors: Francis D. King, Laramie M. Gaster, Alberto J. Kaumann, Rodney C. Young