Patents by Inventor Alberto MINOTTI

Alberto MINOTTI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHETIC AGONISTS OF TLR4 RECEPTOR
    Publication number: 20230037862
    Abstract: The present invention relates to new synthetic molecules with agonist activity of human Toll-like Receptor 4 (TLR4), compositions comprising them and uses thereof for the treatment of diseases in which it is useful to induce or increase an immune response. The compounds have general formula (1), wherein R1 is a saturated C8-C16 aliphatic chain having a ?0 on C1, said chain being free from —OH substituents on C3, wherein R2 is a saturated C8-C16 aliphatic chain having a ?O on C1, said chain being free from —OH substituents on C3, wherein R3 is a saturated C8-C16 aliphatic chain having a ?O on C1, said chain being free from —OH substituents on C3; wherein R4 is a hydrogen atom (H) or a phosphate group (PO42?).
    Type: Application
    Filed: July 18, 2022
    Publication date: February 9, 2023
    Applicant: UNIVERSITÀ DEGLO STUDI DI MILANO - BICOCCA
    Inventors: Francesco PERI, Alberto MINOTTI
  • NEW SYNTHETIC AGONISTS OF TLR4 RECEPTOR
    Publication number: 20210052723
    Abstract: The present invention relates to new synthetic molecules with agonist activity of human Toll-like Receptor 4 (TLR4), compositions comprising them and uses thereof for the treatment of diseases in which it is useful to induce or increase an immune response. The compounds have general formula (1), wherein R1 is a saturated C8-C16 aliphatic chain having a =0 on C1, said chain being free from —OH substituents on C3, wherein R2 is a saturated C8-C16 aliphatic chain having a ?O on C1, said chain being free from —OH substituents on C3, wherein R3 is a saturated C8-C16 aliphatic chain having a ?O on C1, said chain being free from —OH substituents on C3; wherein R4 is a hydrogen atom (H) or a phosphate group (PO42?).
    Type: Application
    Filed: November 5, 2018
    Publication date: February 25, 2021
    Applicant: UNIVERSITA DEGLI STUDI DI MILANO - BICOCCA
    Inventors: Francesco PERI, Alberto MINOTTI