Patent number: 10238679
Abstract: A composition for use in the prevention and/or treatment of colorectal cancer in a patient, comprising: a) a compound of Formula (I), where R1, R2, and R3 are, each one and independently, hydrogen or a protector group, wherein said protector group may consist of an alkyl group, a cycloalkyl group, a heterocyclic cycloalkyl group, a hydroxyalkyl group, a halogenated alkyl group, an alkoxyalkyl group, an alkenyl group, an alkynyl group, an aryl group, a heterocyclic aryl group, an alkylaryl group, an ester group, a carbonate group, a carboxylic acid group, an aldehyde group, a ketone group, a urethane group, a silyl group, a sulfoxide group or a combination thereof; R5, R6, R7, R8, R9 and R10 are, each one and independently, hydrogen, hydroxyl or an —OR4 group, where R4 is a protector group according to the previous definition; and b) at least one chemotherapeutic agent.
Type:
Grant
Filed:
September 24, 2015
Date of Patent:
March 26, 2019
Assignee:
ENTRECHEM, S.L.
Inventors:
Alberto Ocaña Fernández, Atanasio Pandiella Alonso, Francisco Morís Varas
Patent number: 9808469
Abstract: A composition comprising a) a compound of Formula (I), where R1, R2, and R3 are, each one and independently, hydrogen or a protector group, wherein said protector group may consist of an alkyl group, a cycloalkyl group, a heterocyclic cycloalkyl group, a hydroxyalkyl group, a halogenated alkyl group, an alkoxyalkyl group, an alkenyl group, an alkynyl group, an aryl group, a heterocyclic aryl group, an alkylaryl group, an ester group, a carbonate group, a carboxylic acid group, an aldehyde group, a ketone group, a urethane group, a silyl group, a sulfoxide group or a combination thereof, R5, R6, R7, R8, R9 and R10 are, each one and independently, hydrogen, hydroxyl or an —OR4 group, where R4 is a protector group according to the previous definition; and b) at least one chemotherapeutic agent, suitable for use in the treatment of Breast Cancer.
Type:
Grant
Filed:
May 27, 2015
Date of Patent:
November 7, 2017
Assignee:
ENTRECHEM, S.L.
Inventors:
Alberto Ocaña Fernández, Atanasio Pandiella Alonso, Francisco Morís Varas
Publication number: 20170296569
Abstract: A composition for use in the prevention and/or treatment of colorectal cancer in a patient, comprising: a) a compound of Formula (I), where R1, R2, and R3 are, each one and independently, hydrogen or a protector group, wherein said protector group may consist of an alkyl group, a cycloalkyl group, a heterocyclic cycloalkyl group, a hydroxyalkyl group, a halogenated alkyl group, an alkoxyalkyl group, an alkenyl group, an alkynyl group, an aryl group, a heterocyclic aryl group, an alkylaryl group, an ester group, a carbonate group, a carboxylic acid group, an aldehyde group, a ketone group, a urethane group, a silyl group, a sulfoxide group or a combination thereof; R5, R6, R7, R8, R9 and R10 are, each one and independently, hydrogen, hydroxyl or an —OR4 group, where R4 is a protector group according to the previous definition; and b) at least one chemotherapeutic agent.
Type:
Application
Filed:
September 24, 2015
Publication date:
October 19, 2017
Inventors:
Alberto OCANA FERNANDEZ, Atanasio PANDIELLA ALONSO, Francisco MORÍS VARAS
Publication number: 20170196880
Abstract: A composition comprising a) a compound of Formula (I), where R1, R2, and R3 are, each one and independently, hydrogen or a protector group, wherein said protector group may consist of an alkyl group, a cycloalkyl group, a heterocyclic cycloalkyl group, a hydroxyalkyl group, a halogenated alkyl group, an alkoxyalkyl group, an alkenyl group, an alkynyl group, an aryl group, a heterocyclic aryl group, an alkylaryl group, an ester group, a carbonate group, a carboxylic acid group, an aldehyde group, a ketone group, a urethane group, a silyl group, a sulfoxide group or a combination thereof, R5, R6, R7, R8, R9 and R10 are, each one and independently, hydrogen, hydroxyl or an —OR,? group, where R4 is a protector group according to the previous definition; and b) at least one chemotherapeutic agent, suitable for use in the treatment of Breast Cancer.
Type:
Application
Filed:
May 27, 2015
Publication date:
July 13, 2017
Inventors:
Alberto OCAÑA FERNÁNDEZ, Atanasio PANDIELLA ALONSO, Francisco MORÍS VARAS