Patents by Inventor Alberto Roca

Alberto Roca has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acids encoding mutants of MAW motifs of RecA protein homologs
    Patent number: 7294494
    Abstract: RecA protein mutants and RecA homolog protein mutants which contain one or more mutations in the MAW motif are presented. The mutants rely on replacement of wildtype amino acid residues in the MAW motif with specific replacement residues to alter the three-dimensional structure of the MAW motif and to change the protein's DNA-binding properties. Three classes of mutants are described: mutants which will reduce the protein's dependence on ATP to initiate DNA-binding; mutants which more tightly bind DNA; and combination mutants which possess both of these properties.
    Type: Grant
    Filed: June 10, 2004
    Date of Patent: November 13, 2007
    Inventor: Alberto Roca
  • Mutants of MAW motifs of RecA protein homologs method of making them, and their uses
    Publication number: 20050208641
    Abstract: RecA protein mutants and RecA homolog protein mutants which contain one or more mutations in the MAW motif are presented. The mutants rely on replacement of wildtype amino acid residues in the MAW motif with specific replacement residues to alter the three-dimensional structure of the MAW motif and to change the protein's DNA-binding properties. Three classes of mutants are described: mutants which will reduce the protein's dependence on ATP to initiate DNA-binding; mutants which more tightly bind DNA; and combination mutants which possess both of these properties.
    Type: Application
    Filed: June 10, 2004
    Publication date: September 22, 2005
    Inventor: Alberto Roca