Patents by Inventor Alberto Toso

Alberto Toso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREVENTION OR MITIGATION OF NK CELL ENGAGING AGENT-RELATED ADVERSE EFFECTS
    Publication number: 20240058443
    Abstract: The present invention relates to the prevention or mitigation of adverse effects related to NK cell engaging agents, such as cytokine-related infusion reactions. Specifically, the invention relates to the prevention or mitigation of such side effects using an inhibitor of Src, JAK and/or mTOR.
    Type: Application
    Filed: October 20, 2023
    Publication date: February 22, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Hélène Cécile HAEGEL, Christian KLEIN, Gabrielle LECLERCQ, Alberto TOSO, Tina ZIMMERMANN
  • PREVENTION OR MITIGATION OF T-CELL ENGAGING AGENT-RELATED ADVERSE EFFECTS
    Publication number: 20220168418
    Abstract: The present invention relates to the prevention or mitigation of adverse effects related to T cell engaging agents, such as cytokine release syndrome. Specifically, the invention relates to the prevention or mitigation of such side effects using an inhibitor of JAK and/or mTOR.
    Type: Application
    Filed: November 9, 2021
    Publication date: June 2, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Hélène Cécile HAEGEL, Christian KLEIN, Gabrielle LECLERCQ, Alberto TOSO, Tina ZIMMERMANN
  • Prevention or mitigation of T-cell bispecific antibody-related adverse effects
    Publication number: 20220088195
    Abstract: The present invention relates to the prevention or mitigation of adverse effects related to T cell bispecific antibodies, such as cytokine release syndrome. Specifically, the invention relates to the prevention or mitigation of such side effects using a tyrosine kinase inhibitor such as dasatinib.
    Type: Application
    Filed: September 24, 2021
    Publication date: March 24, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Christian Klein, Hélène Cécile Haegel, Alberto Toso, Gabrielle Leclercq, Tina Zimmermann