Abstract: The invention relates to a device for optical detection of substances in a liquid or gaseous medium, with a substrate with molecules for detecting the substances that are to be detected, wherein these molecules are immobilized at a surface of the substrate or in the substrate and wherein the substances that are to be detected can essentially be selectively bound to these molecules, wherein light waves can be coupled into the substrate and can be guided through this, and wherein the substrate is a foil element made of a transparent material in which a coupling structure for coupling the light waves is integrally formed and in which the coupled light waves can be guided.

Abstract: The invention relates to a device for optical detection of substances in a liquid or gaseous medium, with a substrate with molecules for detecting the substances that are to be detected, wherein these molecules are immobilised at a surface of the substrate or in the substrate and wherein the substances that are to be detected can essentially be selectively bound to these molecules, wherein light waves can be coupled into the substrate and can be guided through this, and wherein the substrate is a foil element made of a transparent material in which a coupling structure for coupling the light waves is integrally formed and in which the coupled light waves can be guided.

Abstract: The invention relates to a probe for an optical near field microscope, said probe comprising a planar carrier carrying a probe tip at least partially consisting of a transparent material. The invention also relates to a method of producing one such probe. The object of the invention is to provide a probe for an optical near field microscope and a method for the production thereof, whereby the probe can be produced with high reproducibility according to a simple technology and can have a simple but efficient light supply. According to the invention, the object is solved with a probe of the type mentioned in the introduction such that the carrier comprises an optical waveguide.

Abstract: This invention relates to a probe for an optical near field microscope, said probe comprising a probe tip which is formed on a self-supporting carrier and to a method for producing the same. One object of this invention is to provide a probe for an optical near field microscope and a method of producing the same, whereby the probe has a probe tip with a very small aperture diameter and thus can be reproducibly manufactured in a simple, advantageously controllable method. This object is solved with regard to the probe by a generic probe which is characterised in that the probe tip is embodied as a complete structure which is applied to a planar surface of the carrier.

Abstract: The invention relates to a probe for an optical near field microscope, said probe comprising a planar carrier carrying a probe tip at least partially consisting of a transparent material. The invention also relates to a method of producing one such probe. The object of the invention is to provide a probe for an optical near field microscope and a method for the production thereof, whereby the probe can be produced with high reproducibility according to a simple technology and can have a simple but efficient light supply. According to the invention, the object is solved with a probe of the type mentioned in the introduction such that the carrier comprises an optical waveguide.

Abstract: The present invention relates to a method and a device for determining temperature-dependent parameters, such as the association/dissociation parameters and/or the equilibrium constant of complexes that comprise at least two components, wherein the first components, which are in a liquid phase, are contacted with measuring points located preferably on a planar optical waveguide of a reaction carrier and formed by second components linked to the solid reaction carrier and specifically binding to said first components, with the aid of a preferably heatable means for contacting the liquid phase and the reaction carrier under formation of complexes. Fluorescent dyes bound to the first components and/or the second components are excited in the surface area of the planar optical waveguide, preferably by the evanescent field of excitation light coupled into the planar optical waveguide, for emitting fluorescent light.