Abstract: An implantable biosensor, which comprises a measuring (or first) chamber filled with the test fluid, which is able to convert a change of the concentration of a predetermined analyte or ion type into a change of a physical variable. To this end, the measuring chamber is closed by at least one membrane, which is permeable to the analyte or ion type and impermeable to the test fluid. In addition, the biosensor is equipped with at least one microacoustic sensor, which is operatively connected to the test fluid such that it can detect the physical variable that changes with the concentration of the analyte or ion type. Further relates to a sensor arrangement comprising at least one such implantable biosensor, the arrangement including a polling system that is wirelessly coupled to the biosensor.

Abstract: An implantable medical device has an impedance or admittance determination unit, an alternating current or voltage source, a measuring unit, and an analysis unit which is connected to the alternating current or AC voltage source and the measuring unit to calculate an impedance value or an admittance value at different times. The impedance or admittance determination unit may generate measuring current having two different frequencies (preferably below 100 kHz), and the analysis unit may calculate pairs of impedance or admittance values which are chronologically assigned to one another for different frequencies of the measuring current, and calculate a value for a blood impedance or blood admittance component which is independent of the impedance of the body tissue surrounding a particular blood vessel, The analysis unit may also determine trends in this value over time as an indicator for a change of blood hematocrit value.

Abstract: A method and an arrangement for creating an individualized, computer-aided model of a system, for determining physiological variables and/or parameters from clinical measurements and continuous measurements. Furthermore, one or more embodiments makes it possible to detect disease-related changes, to the heart in particular, and enables an improved medical interpretation of measurements by implant sensors. The system is not limited to physiological systems, and can also be used to monitor technical systems.

Abstract: A method for automatic registration of a patient-bound medical device with a remote data processing system, physician identification data being transmitted to the patient-bound medical device, the physician identification data being combined together with device identification data to form a registration message, the registration message being transmitted from the patient-bound medical device to the data processing system, and the data processing system checking the data contained in the registration message and, in case of success, performing the registration, as well as apparatuses for this purpose.

Abstract: An implantable biosensor, which comprises a measuring (or first) chamber filled with the test fluid, which is able to convert a change of the concentration of a predetermined analyte or ion type into a change of a physical variable. To this end, the measuring chamber is closed by at least one membrane, which is permeable to the analyte or ion type and impermeable to the test fluid. In addition, the biosensor is equipped with at least one microacoustic sensor, which is operatively connected to the test fluid such that it can detect the physical variable that changes with the concentration of the analyte or ion type. Further relates to a sensor arrangement comprising at least one such implantable biosensor, the arrangement including a polling system that is wirelessly coupled to the biosensor.

Abstract: An implantable medical device has an impedance or admittance determination unit, an alternating current or voltage source, a measuring unit, and an analysis unit which is connected to the alternating current or AC voltage source and the measuring unit to calculate an impedance value or an admittance value at different times. The impedance or admittance determination unit may generate measuring current having two different frequencies (preferably below 100 kHz), and the analysis unit may calculate pairs of impedance or admittance values which are chronologically assigned to one another for different frequencies of the measuring current, and calculate a value for a blood impedance or blood admittance component which is independent of the impedance of the body tissue surrounding a particular blood vessel, The analysis unit may also determine trends in this value over time as an indicator for a change of blood hematocrit value.

Abstract: A method for automatic registration of a patient-bound medical device with a remote data processing system, physician identification data being transmitted to the patient-bound medical device, the physician identification data being combined together with device identification data to form a registration message, the registration message being transmitted from the patient-bound medical device to the data processing system, and the data processing system checking the data contained in the registration message and, in case of success, performing the registration, as well as apparatuses for this purpose.

Abstract: A data management system for processing of physiological or technical data or both to generate a display control signal is disclosed. The data system comprises a data interface having a patient data interface and a user interface. The patient data interface is adapted to receive data which represent physiological parameters of a patient or technical parameters of a medical device, in particular of an implant such as a cardiac pacemaker, defibrillator, or cardioverter, for example. The user interface is adapted to receive data to be entered by a user. The user interface may be a keyboard or a touch screen or a voice interface, for example.