Patents by Inventor Aldo Giannozzi

Aldo Giannozzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED SACCHARIDES, CONJUGATES THEREOF, AND THEIR MANUFACTURE
    Publication number: 20150166593
    Abstract: Saccharide-protein conjugates having a new type of linker are described. The conjugates comprising the new linker are prepared from modified saccharides comprising a moiety of the formula (I): -A-N(R1)-L-M wherein: A is a bond, —C(O)— or —OC(O)—; R1 is selected from H or C1-C6 alkyl; L is a C1-C12 alkylene group; and M is a masked aldehyde group. The new linker is especially useful for preparing conjugates of Neisseria meningitidis serogroup A saccharide. Conjugates having this new linker have improved immunogenicity compared to other types of conjugates.
    Type: Application
    Filed: October 23, 2014
    Publication date: June 18, 2015
    Inventors: Aldo GIANNOZZI, Giovanni AVERANI, Francesco NORELLI, Paolo CONSTANTINO
  • Modified saccharides, conjugates thereof, and their manufacture
    Patent number: 8895516
    Abstract: Saccharide-protein conjugates having a new type of linker are described. The conjugates comprising the new linker are prepared from modified saccharides comprising a moiety of the formula (I): -A-N(R1)-L-M wherein: A is a bond, —C(O)— or —OC(O)—; R1 is selected from H or C1-C6 alkyl; L is a C1-C12 alkylene group; and M is a masked aldehyde group. The new linker is especially useful for preparing conjugates of Neisseria meningitidis serogroup A saccharide. Conjugates having this new linker have improved immunogenicity compared to other types of conjugates.
    Type: Grant
    Filed: September 1, 2003
    Date of Patent: November 25, 2014
    Assignee: Novartis AG
    Inventors: Aldo Giannozzi, Giovanni Averani, Francesco Norelli, Paolo Costantino
  • Modified saccharides, conjugates thereof, and their manufacture
    Publication number: 20060263390
    Abstract: Saccharide-protein conjugates having a new type of linker are described. The conjugates comprising the new linker are prepared from modified saccharides comprising a moiety of the formula (I): -A-N(R1)-L-M wherein: A is a bond, —C(O)— or —OC(O)—; R1 is selected from H or C1-C6 alkyl; L is a C1-C12 alkylene group; and M is a masked aldehyde group. The new linker is especially useful for preparing conjugates of Neisseria meningitidis serogroup A saccharide. Conjugates having this new linker have improved immunogenicity compared to other types of conjugates.
    Type: Application
    Filed: September 1, 2003
    Publication date: November 23, 2006
    Inventors: Aldo Giannozzi, Giovanni Averani, Francesco Norelli, Paolo Costantino
  • Combined meningitis vaccine
    Patent number: 6251401
    Abstract: A combined vaccine for bacterial meningitis comprises Hib and MenC oligosaccharide conjugates.
    Type: Grant
    Filed: May 1, 1997
    Date of Patent: June 26, 2001
    Assignee: Chiron S.p.A.
    Inventors: Costante Ceccarini, Paolo Costantino, Sandro D'Ascenzi, Francesco Norelli, Aldo Giannozzi