Patents by Inventor Alec BROZELL

Alec BROZELL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE ALK5 INHIBITORS AND USES THEREOF
    Publication number: 20210387983
    Abstract: The present disclosure provides crystalline forms of activin receptor-like kinase 5 (ALK5) inhibitors. Also disclosed are pharmaceutical compositions comprising the crystalline forms, methods of using the crystalline forms to modulate the activity of ALK5 and methods of treating disorders mediated by ALK5 using the crystalline forms.
    Type: Application
    Filed: June 9, 2021
    Publication date: December 16, 2021
    Applicant: THERAVANCE BIOPHARMA R&D IP, LLC
    Inventors: Alec Brozell, Marta Dabros, Jing Fu, Miroslav Rapta
  • Methods for preparing levorphanol and related compounds, and compositions thereof
    Patent number: 10851063
    Abstract: A method for producing substantially pure levorphanol and related compounds, when compared to the conventional process, is provided. In particular, a method for producing substantially pure levorphanol tartrate dihydrate is described. Also described are compositions comprising levorphanol and related compounds, particularly compositions comprising levorphanol tartrate dihydrate, levomethorphan, and norlevorphanol in which the levomethorphan and norlevorphanol are present in the composition in reduced levels.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: December 1, 2020
    Assignee: AMPAC FINE CHEMICALS LLC
    Inventors: William Dubay, Alex Nichols, Wei Chen, Alec Brozell, Ajay Ryerson
  • METHODS FOR PREPARING LEVORPHANOL AND RELATED COMPOUNDS, AND COMPOSITIONS THEREOF
    Publication number: 20200109119
    Abstract: A method for producing substantially pure levorphanol and related compounds, when compared to the conventional process, is provided. In particular, a method for producing substantially pure levorphanol tartrate dihydrate is described. Also described are compositions comprising levorphanol and related compounds, particularly compositions comprising levorphanol tartrate dihydrate, levomethorphan, and norlevorphanol in which the levomethorphan and norlevorphanol are present in the composition in reduced levels.
    Type: Application
    Filed: October 4, 2018
    Publication date: April 9, 2020
    Inventors: William DUBAY, Alex NICHOLS, Wei CHEN, Alec BROZELL, Ajay RYERSON