Patents by Inventor Alec Drake WITTY

Alec Drake WITTY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR GENERATING EPICARDIUM CELLS
    Publication number: 20210062153
    Abstract: Methods and products for obtaining cardiovascular lineage cells from hPSCs. The method comprises one or more of the following steps: (a) contacting BMP component primed hPSCs with a cardiovascular mesoderm programming cocktail and culturing the contacted hPSCs for a period of time to generate a KDR+ and PDGFRalpha+ cardiovascular mesoderm cell population; (b) contacting the cardiovascular mesoderm cell population with a cardiovascular progenitor specification cocktail and culturing the contacted cardiovascular mesoderm cell population for a period of time to generate a NKX2-5+ or WT1+ cardiovascular progenitor cell population; and (c) contacting the cardiovascular progenitor cell population with a maturation cocktail and culturing the contacted cardiovascular progenitor population for a period of time to produce a cardiovascular population optionally cardiomyocyte lineage cells expressing cardiac troponin T (cTnT) and/or SIRPA and/or epicardial lineage cells expressing WT1.
    Type: Application
    Filed: June 14, 2020
    Publication date: March 4, 2021
    Inventors: Gordon Keller, Alec Drake Witty, Steven James Kattman
  • Methods and compositions for generating epicardium cells
    Patent number: 10711246
    Abstract: Provided are methods and products for obtaining cardiovascular lineage cells from hPSCs.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: July 14, 2020
    Assignee: UNIVERSITY HEALTH NETWORK
    Inventors: Gordon Keller, Alec Drake Witty, Steven James Kattman
  • METHODS AND COMPOSITIONS FOR GENERATING EPICARDIUM CELLS
    Publication number: 20160215263
    Abstract: Provided are methods and products for obtaining cardiovascular lineage cells from hPSCs.
    Type: Application
    Filed: September 12, 2014
    Publication date: July 28, 2016
    Inventors: Gordon KELLER, Alec Drake WITTY, Steven James KATTMAN