Patents by Inventor Alec John Jeffreys

Alec John Jeffreys has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6235468
    Abstract: A method of characterizing a test sample of genomic DNA which method comprises contacting the test sample with type specific primer to prime selectively, within a telomere repeat array, internal repeat units of that type, and extending the type specific primers in the presence of appropriate nucleoside triphosphates and an agent for polymerization thereof to produce a set of amplification products extending from the internal repeat units of that type to at least the end of the telomere repeat array.
    Type: Grant
    Filed: April 16, 1997
    Date of Patent: May 22, 2001
    Assignee: Zeneca Limited
    Inventors: Duncan Martin Baird, Nicola Jane Royle, Alec John Jeffreys
  • Patent number: 5853989
    Abstract: The present invention relates generally to a method of characterizing a sample of genomic DNA and to nucleotide sequences employed in the method as well as kits comprising these. In particular the invention involves the use of primers which selectively prime specific type(s) of internal repeat unit in a tandemly repeated region. The method of the invention is particularly useful in forensic or paternity studies and provides individual sample codes suitable for computerized storage on, and retrieval from, a database.
    Type: Grant
    Filed: May 6, 1996
    Date of Patent: December 29, 1998
    Assignee: Zeneca Limited
    Inventors: Alec John Jeffreys, Stephen Little, Richard Mark Ferrie, Jannine Brownie
  • Patent number: 5843647
    Abstract: The present invention concerns a method for the identification from DNA of a fragment comprising a simple tandem repeat locus comprising the steps of:i) contacting a DNA library with at least one hybridisation probe so as to identify a population of DNA fragments enriched for simple tandem repeats;ii) isolating and cloning said population; andiii) screening of the resulting DNA library so as to identify an individual fragment comprising a simple tandem repeat locus.Also provided are simple tandem repeats isolated by the method of the present invention, characterised in that they may be amplified at least in part by PCR using a specified pair of primers, together with amplification primers and probes specific to the simple tandem repeats so isolated.The present invention also provides methods of genetic characterisation using the aforementioned simple tandem repeats, primers and probes.
    Type: Grant
    Filed: November 1, 1994
    Date of Patent: December 1, 1998
    Assignee: University of Leicester
    Inventors: Alec John Jeffreys, John Armour
  • Patent number: 5811235
    Abstract: A method of characterizing a test sample of genomic DNA which method comprises amplifying a tandemly repeated region, comprising more than one type of repeat unit, as far as internal repeat units of a specific type so as to generate a set of amplification products which identify the relative positions of the internal repeat units within the tandemly repeated region, and separating the set of amplification products to provide a sample code. The sample codes are suitable for computerized storage on, and retrieval from, a database. The invention also provides a novel method for the detection of diagnostic base sequences in one or more nucleic acids contained in a sample.
    Type: Grant
    Filed: April 5, 1995
    Date of Patent: September 22, 1998
    Assignee: Zeneca Limited
    Inventor: Alec John Jeffreys