Abstract: A method and system for geo-localization in sensor-deprived or sensor-limited environments includes receiving an image file for geo-localization of a location depicted by the image file in a sensor-deprived environment; applying a plurality of geo-localization modules to the image file; generating, by each of the plurality of geo-localization modules, a module output, each module output including a module geolocation for the location and a module confidence score for the module geolocation; generating an ensemble geolocation output, the ensemble geolocation output including an ensemble geolocation for the location and an ensemble confidence score for the ensemble geolocation, the ensemble geolocation output being a weighted combination of the module outputs; and displaying the ensemble geolocation output to a display.

Abstract: Methods of prophylactically treating fibrotic conditions using a synthetic lamellar body composition are provided, such as conditions of the lung, skin, gastrointestinal system, genitourinary system, heart, peritoneum, kidney, liver, and mucosa. In particular the present invention is concerned with lung injury which may be characterised by increased pulmonary vascular permeability. Suitably the lamellar body composition for use in the prophylactic treatment of fibrotic or pro-fibrotic conditions comprises phosphatidylcholine, cholesterol and optionally at least one phospholipid selected from phosphatidyl serine, phosphatidyl glycerol and phosphatidyl inositol to provide an anionic lamellar body.

Abstract: Biofilm production, which provides microbes with a multi-layered structured community attached to a surface and encased within a matrix of exopolymeric material, is associated with up-regulated virulence of infection and can limit the immune system response and/or the effectiveness of therapeutic agents. The use of lamellar bodies to modulate quorum sensing to inhibit or reduce biofilm production and for treatment of microbial infections is provided.