Patents by Inventor Alec WITTY

Alec WITTY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED iPSC AND ARMED IMMUNE EFFECTOR CELLS
    Publication number: 20240033355
    Abstract: Provided are methods and compositions for obtaining functionally enhanced derivative effector cells obtained from directed differentiation of genomically engineered iPSCs. The iPSC-derived cells provided herein have stable and functional genome editing that delivers improved or enhanced therapeutic effects. Also provided are therapeutic compositions and the use thereof comprising the functionally enhanced derivative effector cells alone, or with antibodies or checkpoint inhibitors in combination therapies.
    Type: Application
    Filed: October 8, 2021
    Publication date: February 1, 2024
    Inventors: Dan LU, Bahram VALAMEHR, Eigen PERALTA, Tom LEE, Alec WITTY
  • CD3 RECONSTITUTION IN ENGINEERED iPSC AND IMMUNE EFFECTOR CELLS
    Publication number: 20220184142
    Abstract: Provided are methods and compositions for obtaining functionally enhanced derivative effector cells obtained from directed differentiation of genomically engineered iPSCs. The iPSC-derived cells provided herein have stable and functional genome editing that delivers improved or enhanced therapeutic effects. Also provided are therapeutic compositions and the used thereof comprising the functionally enhanced derivative effector cells alone, or with antibodies or checkpoint inhibitors in combination therapies.
    Type: Application
    Filed: April 8, 2020
    Publication date: June 16, 2022
    Inventors: Bahram VALAMEHR, Tom Tong LEE, Alec WITTY, Mochtar PRIBADI