Patents by Inventor Alejandra E. Arbetman

Alejandra E. Arbetman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AAV VIRIONS WITH DECREASED IMMUNOREACTIVITY AND USES THEREFOR
    Publication number: 20220016264
    Abstract: Methods of making and using recombinant AAV virions with decreased immunoreactivity are described. The recombinant AAV virions include mutated capsid proteins or are derived from non-primate mammalian AAV serotypes and isolates that display decreased immunoreactivity relative to AAV-2.
    Type: Application
    Filed: June 23, 2021
    Publication date: January 20, 2022
    Inventors: Alejandra E. ARBETMAN, Peter C. COLOSI, Michael A. LOCHRIE, Richard T. SUROSKY
  • AAV virions with decreased immunoreactivity and uses therefor
    Patent number: 11083800
    Abstract: Methods of making and using recombinant AAV virions with decreased immunoreactivity are described. The recombinant AAV virions include mutated capsid proteins or are derived from non-primate mammalian AAV serotypes and isolates that display decreased immunoreactivity relative to AAV-2.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: August 10, 2021
    Assignee: Genzyme Corporation
    Inventors: Alejandra E. Arbetman, Peter C. Colosi, Michael A. Lochrie, Richard T. Surosky
  • AAV VIRIONS WITH DECREASED IMMUNOREACTIVITY AND USES THEREFOR
    Publication number: 20190314526
    Abstract: Methods of making and using recombinant AAV virions with decreased immunoreactivity are described. The recombinant AAV virions include mutated capsid proteins or are derived from non-primate mammalian AAV serotypes and isolates that display decreased immunoreactivity relative to AAV-2.
    Type: Application
    Filed: January 29, 2019
    Publication date: October 17, 2019
    Inventors: Alejandra E. ARBETMAN, Peter C. COLOSI, Michael A. LOCHRIE, Richard T. SUROSKY
  • AAV vectors for gene delivery to the lung
    Patent number: 8007780
    Abstract: Methods of making and using recombinant AAV vectors and virions for gene delivery to the lung are described. The recombinant AAV virions are derived from caprine AAV and bovine AAV, both of which display tropism for lung tissue.
    Type: Grant
    Filed: May 23, 2008
    Date of Patent: August 30, 2011
    Assignee: Genzyme Corporation
    Inventors: Alejandra E. Arbetman, Michael A. Lochrie
  • AAV vectors for gene delivery to the lung
    Publication number: 20080292595
    Abstract: Methods of making and using recombinant AAV vectors and virions for gene delivery to the lung are described. The recombinant AAV virions are derived from caprine AAV and bovine AAV, both of which display tropism for lung tissue.
    Type: Application
    Filed: May 23, 2008
    Publication date: November 27, 2008
    Inventors: Alejandra E. Arbetman, Michael A. Lochrie
  • AAV vectors for gene delivery to the lung
    Patent number: 7427396
    Abstract: Methods of making and using recombinant AAV vectors and virions for gene delivery to the lung are described. The recombinant AAV virions are derived from caprine AAV and bovine AAV, both of which display tropism for lung tissue.
    Type: Grant
    Filed: June 2, 2005
    Date of Patent: September 23, 2008
    Assignee: Genzyme Corporation
    Inventors: Alejandra E. Arbetman, Michael A. Lochrie