Patents by Inventor Alejandro Abuin

Alejandro Abuin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically Engineered and Phenotyped Mice and Stem Cell Clones for Producing the Same
    Publication number: 20090193532
    Abstract: The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides methods for using the mice, cells, polynucleotides, polypeptides and antibodies of the invention.
    Type: Application
    Filed: April 8, 2008
    Publication date: July 30, 2009
    Inventors: Alejandro Abuin, Joel A. Edwards, Charles Montgomery, Carolina Rangel, Arthur T. Sands, Zheng-Zheng Shi, Mary Jean Sparks, Peter Vogel, Brian Zambrowicz
  • Genetically Engineered and Phenotyped Mice and Stem Cell Clones for Producing the Same
    Publication number: 20090113564
    Abstract: The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides methods for using the mice, cells, polynucleotides, polypeptides and antibodies of the invention.
    Type: Application
    Filed: March 28, 2008
    Publication date: April 30, 2009
    Inventors: Alejandro Abuin, Mark Dominic Borromeo, Katherin E. Combs, Ling Ling Culbertson, Zhi-Yong Ding, Joel Edwards, Liangfen Fan, Rosemary Girgis, Leslie Jane Green, Allison Anne Byers Horner, Erin Marie Massey, Dina Rebecca McLain, Laurie Jeanette Minze, Charles Montgomery, Bobby Joe Payne, Carolina Rangel, Arthur T. Sands, Tracy Ellen Willis Sevaux, Zheng-Zheng Shi, Mary Jean Sparks, Joy Anne Stala, Peter Vogel, Brian Zambrowicz
  • Genetically Engineered and Photyped Mice and Stem Cell Clones for Producing the Same
    Publication number: 20090077680
    Abstract: The current invention relates to genetically engineered mice, cells derived from those mice, and polynucleotides and polypeptides corresponding to genes affected by the engineered mutation. The invention also relates to antibodies raised in a mouse of the invention. The invention further provides methods for using the mice, cells, polynucleotides, polypeptides and antibodies of the invention.
    Type: Application
    Filed: April 8, 2008
    Publication date: March 19, 2009
    Inventors: Alejandro Abuin, Joel Edwards, Charles Montgomery, Bobby Joe Payne, Carolina Rangel, Arthur T. Sands, Zheng-Zheng Shi, Mary Jean Sparks, Teresa Gail Townsend, Rosemary Girgis, Allison Anne Byers Horner, Peter Vogel, Brian Zambrowicz
  • Novel human membrane proteins and polynucleotides encoding the same
    Publication number: 20080102520
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: February 17, 2006
    Publication date: May 1, 2008
    Inventors: Alejandro Abuin, Michael B. Burnett, Emily B. Cullinan, Gregory Donoho, Dorit B. Donoviel, Carl Johan Friddle, Glenn Friedrich, Brenda Gerhardt, Erin Hilbun, Yi Hu, Brian Mathur, Maricar Miranda, Michael C. Nehls, Boris Nepomnichy, David George Potter, David Reed Powell, Arthur T. Sands, John Scoville, Hong Sun, C. Alexander Turner, D. Wade Walke, Frank Wattler, Nathaniel L. Wilganowski, Xuanchuan Yu, Brian Zambrowicz
  • Novel human kinases and polynucleotides encoding the same
    Publication number: 20080050809
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: June 23, 2005
    Publication date: February 28, 2008
    Inventors: Alejandro Abuin, Gregory Donoho, Carl Johan Friddle, Glenn Friedrich, Brenda Gerhardt, Erin Hilbun, Yi Hu, James Alvin Kieke, Brian Mathur, Daniel Mathur, Maricar Miranda, Michael C. Nehls, Boris Nepomnichy, Arthur T. Sands, John Scoville, C. Alexander Turner, D. Wade Walke, Xiaoming Wang, Nathaniel L. Wilganowski, Amy Qiongshu Xie, Xuanchuan Yu, Brian Zambrowicz
  • Novel human proteases and polynucleotides encoding the same
    Publication number: 20080003673
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: September 6, 2005
    Publication date: January 3, 2008
    Inventors: Alejandro Abuin, Gregory Donoho, Carl Friddle, Glenn Friedrich, Brenda Gerhardt, Erin Hilbun, Yi Hu, James Kieke, Maricar Miranda, Michael Nehls, Boris Nepomnichy, Andrew Olson, Arthur Sands, John Scoville, C. Turner, D. Walke, Nathaniel Wilganowski, Xuanchuan Yu, Brian Zambrowicz
  • Novel human membrane proteins and polynucleotides encoding the same
    Publication number: 20070298489
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: October 5, 2005
    Publication date: December 27, 2007
    Inventors: Alejandro Abuin, Michael Burnett, Gregory Donoho, Carl Friddle, Glenn Friedrich, Brenda Gerhardt, Erin Hilbun, Yi Hu, Brian Mathur, Michael Nehls, Boris Nepomnichy, Arthur Sands, John Scoville, C. Turner, D. Walke, Xiaoming Wang, Frank Wattler, Nathaniel Wilganowski, Brian Zambrowicz
  • Novel human enzymes and polynucleotides encoding the same
    Publication number: 20060063245
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: September 15, 2005
    Publication date: March 23, 2006
    Inventors: D. Walke, Nathaniel Wilganowski, C. Turner, Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur Sands
  • Novel mutated mammalian cells and animals
    Publication number: 20060031947
    Abstract: Novel mutated mammalian cells are provided that have been characterized by identifying the sequence of the genes that have been mutated. Preferably, novel mutated cells are murine ES cells that stably incorporate retroviral gene trap constructs in the specifically identified genes. The novel mutated cells and animals are useful in functional genomic analysis, and in the discovery and development of new therapeutic and diagnostics agents and methods.
    Type: Application
    Filed: December 23, 2004
    Publication date: February 9, 2006
    Inventors: Alejandro Abuin, Brian Zambrowicz, Arthur Sands
  • Novel human transferase proteins and polynucleotides encoding the same
    Publication number: 20050287568
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: May 20, 2005
    Publication date: December 29, 2005
    Inventors: Gregory Donobo, Erin Hilbun, C. Turner, Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur Sands, D. Walke, Nathaniel Wilganowski, Yi Hu, James Kieke, David Potter
  • Novel human membrane protein and polynucleotides encoding the same
    Publication number: 20050261488
    Abstract: The nucleotide and amino acid sequences of a novel human G protein-coupled receptor (NGPCR) is disclosed. The NGPCR is somewhat similar to human latrophilin, lectomedin, and serpentine, proteins, among others.
    Type: Application
    Filed: March 31, 2005
    Publication date: November 24, 2005
    Inventors: D. Walke, Nathaniel Wilganowski, C. Turner, Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur Sands
  • Noved human proteases and polynucleotides encoding the same
    Publication number: 20050222401
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: January 10, 2005
    Publication date: October 6, 2005
    Inventors: Gregory Donoho, John Scoville, C. Turner, Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur Sands
  • Novel human proteases and polynucleotides encoding the same
    Publication number: 20050214783
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: July 12, 2004
    Publication date: September 29, 2005
    Inventors: D. Walke, C. Turner, Alejandro Abuin, Glenn Friedrich, Brian Zambrowicz, Arthur Sands
  • Novel human phosphatases and polynucleotides encoding the same
    Publication number: 20050208571
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: May 12, 2005
    Publication date: September 22, 2005
    Inventors: D. Walke, John Scoville, C. Turner, Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur Sands
  • Human transferase proteins and polynucleotides encoding the same
    Patent number: 6929937
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: February 11, 2003
    Date of Patent: August 16, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: C. Alexander Turner, Jr., Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur T. Sands, D. Wade Walke, Nathaniel L. Wilganowski
  • Methods and compositions for defining gene function
    Publication number: 20050118710
    Abstract: A process for producing and analyzing insertionally mutated cell clones is provided. Cells incorporating insertional mutations are provided. A collection of insertionally mutated cell clones is also provided.
    Type: Application
    Filed: September 30, 2004
    Publication date: June 2, 2005
    Inventors: Gwenn Hansen, Alejandro Abuin, Brian Zambrowicz, Carl Friddle, William Dempsey
  • Novel human neurexin-like proteins and polynucleotides encoding the same
    Publication number: 20050096462
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: November 29, 2004
    Publication date: May 5, 2005
    Inventors: C. Turner, Erin Hilbun, Gregory Donoho, John Scoville, Frank Wattler, Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur Sands
  • Novel human phospholipases and polynucleotides encoding the same
    Publication number: 20050089886
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: June 4, 2004
    Publication date: April 28, 2005
    Inventors: Yi Hu, Boris Nepomnichy, Gregory Donoho, Erin Hilbun, C. Turner, Alejandro Abuin, Glenn Friedrich, Brian Zambrowicz, Arthur Sands
  • Human proteases and polynucleotides encoding the same
    Patent number: 6881563
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Grant
    Filed: January 28, 2004
    Date of Patent: April 19, 2005
    Assignee: Lexicon Genetics Incorporated
    Inventors: Gregory Donoho, John Scoville, C. Alexander Turner, Jr., Glenn Friedrich, Alejandro Abuin, Brian Zambrowicz, Arthur T. Sands
  • Novel human kinase proteins and polynucleotides encoding the same
    Publication number: 20050079530
    Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
    Type: Application
    Filed: September 8, 2004
    Publication date: April 14, 2005
    Inventors: Gregory Donoho, John Scoville, C. Turner, Glenn Friedrich, Brian Zambrowicz, Alejandro Abuin, Arthur Sands