Patents by Inventor Alejandro Berra

Alejandro Berra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9427354
    Abstract: This invention relates to a material for medical use that comprises biocompatible nanoparticles having superparamagnetic properties, where the superparamagnetic properties of said nanoparticles are used to localize their action on a determined space or tissue. In particular, said nanoparticles having superparamagnetic properties are composed of magnetite. The material according to the invention has various applications, both in surgical and in therapeutic treatments.
    Type: Grant
    Filed: September 9, 2011
    Date of Patent: August 30, 2016
    Assignee: NANOPHTHALMICS, LLC
    Inventors: Roberto Zysler, Alejandro Berra, Pablo Gurman, Orlando Hector Auciello, Mario Joaquin Saravia
  • Patent number: 9187518
    Abstract: A method of treating a solid tumor in a mammal by inhibiting angiogenesis, including administering to the mammal which has a solid tumor selected from the group consisting of breast carcinoma, lung carcinoma, prostate carcinoma, colon carcinoma, ovarian carcinoma, neuroblastoma, central nervous system tumor, multiform glioblastoma and melanoma; a composition including brassinosteroids of general formula (I) wherein can be a single or double bond and the configurations of carbon atoms C22 and C23 respectively linked to the substituents HO are S for both carbon atoms and a pharmaceutically acceptable additive.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: November 17, 2015
    Assignees: CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET), INIS BIOTECH LLC
    Inventors: Javier Alberto Ramirez, Flavia Mariana Michelini, Lydia Raquel Galagovsky, Alejandro Berra, Laura Edith Alche
  • Publication number: 20150094288
    Abstract: A method of treating a solid tumor in a mammal by inhibiting angiogenesis, including administering to the mammal which has a solid tumor selected from the group consisting of breast carcinoma, lung carcinoma, prostate carcinoma, colon carcinoma, ovarian carcinoma, neuroblastoma, central nervous system tumor, multiform glioblastoma and melanoma; a composition including brassinosteroids of general formula (I) wherein can be a single or double bond and the configurations of carbon atoms C22 and C23 respectively linked to the substituents HO are S for both carbon atoms and a pharmaceutically acceptable additive.
    Type: Application
    Filed: December 14, 2012
    Publication date: April 2, 2015
    Applicant: CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECHNICAS (CONICET)
    Inventors: Javier Alberto Ramirez, Flavia Mariana Michelini, Lydia Raquel Galagovsky, Alejandro Berra, Laura Edith Alche
  • Patent number: 8834757
    Abstract: The invention provides a method for producing bioinert biocompatible diamond particles/polymer composites or any other matrix (e.g. glass, metal, plastic, ceramic and more)/diamond particle composites, even if not biocompatible with outstanding mechanical, tribological, and biological properties, the method comprising selecting a polymer having a melting temperature below about 300 C; mixing diamond particles with the polymer to form a liquid mixture, poring the liquid diamond particle/polymer or any other diamond particle/matrix composite in liquid form into a mold and then causing the composite to sinter with the diamond particles densely and uniformly distributed through the bulk and surface of the composite, such that the diamond particles distributed on the surface can form a diamond layer covering the surface.
    Type: Grant
    Filed: September 30, 2011
    Date of Patent: September 16, 2014
    Assignee: UChicago Argonne, LLC
    Inventors: Orlando H. Auciello, Pablo Gurman, Alejandro Berra
  • Publication number: 20130225906
    Abstract: This invention relates to a material for medical use that comprises biocompatible nanoparticles having superparamagnetic properties, where the superparamagnetic properties of said nanoparticles are used to localize their action on a determined space or tissue. In particular, said nanoparticles having superparamagnetic properties are composed of magnetite. The material according to the invention has various applications, both in surgical and in therapeutic treatments.
    Type: Application
    Filed: September 9, 2011
    Publication date: August 29, 2013
    Applicant: NANOPHTHALMICS, LLC
    Inventors: Roberto Zysler, Alejandro Berra, Pablo Gurman, Orlando Auciello, Mario Joaquin Saravia
  • Patent number: 8431554
    Abstract: Brassinosteriods, illustrated by the following exemplary compounds, are disclosed: The compounds have anti-inflammatory and antiviral activity. In pharmaceutical compositions, the compounds are useful in ophthalmic pharmaceuticals for treatment of diseases caused by adenovirus, such as epidemic keratoconjunctivitis, and herpes simplex type 1, such as herpetic stromal keratitis.
    Type: Grant
    Filed: July 4, 2008
    Date of Patent: April 30, 2013
    Assignees: Consejo Nacional de Investigaciones Cientificas y Tecnicas (Conicet), Inis Biotech LLC
    Inventors: Javier Alberto Ramirez, Flavia Mariana Michelini, Lydia Raquel Galagovsky, Alejandro Berra, Laura Edith Alche
  • Publication number: 20130084420
    Abstract: The invention provides a method for producing bioinert biocompatible diamond particles/polymer composites or any other matrix (e.g. glass, metal, plastic, ceramic and more)/diamond particle composites, even if not biocompatible with outstanding mechanical, tribological, and biological properties, the method comprising selecting a polymer having a melting temperature below about 300 C; mixing diamond particles with the polymer to form a liquid mixture, poring the liquid diamond particle/polymer or any other diamond particle/matrix composite in liquid form into a mold and then causing the composite to sinter with the diamond particles densely and uniformly distributed through the bulk and surface of the composite, such that the diamond particles distributed on the surface can form a diamond layer covering the surface.
    Type: Application
    Filed: September 30, 2011
    Publication date: April 4, 2013
    Applicant: UCHICAGO ARGONNE, LLC
    Inventors: Orlando H. Auciello, Pablo Gurman, Alejandro Berra
  • Publication number: 20100120735
    Abstract: The present invention refers to a compound having anti-inflammatory and antiviral activity according to the following structural formula: wherein, R1 and R3 are selected from H, HO—, R5—O—, HCOO—, R5—COO—, —OOC—R6—COO—, p-toluene sulphonate, phosphate, tartrate, maleate, sulphate, fluorine, chlorine, bromine, iodine and methanesulphonate, R2 is selected from H, HO—, R5—O—, HCOO—, R5—COO—, —OOC—R6—COO—, p-toluene sulphonate, phosphate, tartrate, maleate, sulphate, fluorine, chlorine, bromine, and iodine, or —R1 and —R2 can be together —O—, (CH3)2—(CO)2-(ó-(CH3—CH2)2—(CO)2— R4 and R5 are selected from H and linear or branched C1-C4 alkyl, R6 is —(CH2)n equals to 1, 2 ó 3, and, can be a single bond or double bond, to the pharmaceutical compositions comprising the same, to a process for preparing the same and to the use of the same for preparing pharmaceutical compositions.
    Type: Application
    Filed: July 4, 2008
    Publication date: May 13, 2010
    Applicants: Consejo Nacional de Investigaciones Cientificas Y Tecnicas (Conicet), Inis Biotech LLC
    Inventors: Javier Alberto Ramirez, Flavia Mariana Michelini, Lydia Raquel Galagovsky, Alejandro Berra, Laura Edith Alche