Patents by Inventor Alejandro Carpy Gutierrez Cirlos

Alejandro Carpy Gutierrez Cirlos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNE ACTIVATING Fc DOMAIN BINDING MOLECULES
    Publication number: 20240043535
    Abstract: The present invention generally relates to novel immune activating Fc domain binding molecules for activation of immune cells and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.
    Type: Application
    Filed: December 16, 2022
    Publication date: February 8, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Maria Amann, Alejandro Carpy Gutierrez Cirlos, Christina Claus, Laura Codarri Deak, Diana Darowski, Tanja Fauti, Claudia Ferrara Koller, Anne Freimoser-Grundschober, Sylvia Herter, Thomas Hofer, Christian Klein, Laura Lauener, Stephane Leclair, Ekkehard Moessner, Christiane Neumann, Pablo Umaña, Ali Bransi, Marlena Surówka
  • ANTIBODIES BINDING TO CD3 AND PLAP
    Publication number: 20240018240
    Abstract: The present invention generally relates to antibodies that bind to CD3 and PLAP, e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
    Type: Application
    Filed: December 8, 2022
    Publication date: January 18, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Ali Bransi, Alejandro Carpy Gutierrez Cirlos, Anne Freimoser-Grundschober, Kerstin Hofer, Thomas Hofer, Tommy Kuehnl, Ekkehard Moessner, Christiane Neumann
  • PROTEASE-ACTIVATED T CELL BISPECIFIC ANTIBODIES
    Publication number: 20230287145
    Abstract: The present invention generally relates to novel protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides. The present invention also relates to polynucleotides encoding such protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides of the invention, and to methods of using these protease-activatable T cell activating bispecific molecules and idiotype-specific polypeptides in the treatment of disease.
    Type: Application
    Filed: December 15, 2022
    Publication date: September 14, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Peter BRUENKER, Alejandro CARPY GUTIERREZ CIRLOS, Anne FREIMOSER-GRUNDSCHOBER, Martina GEIGER, Thomas HOFER, Christian KLEIN, Ekkehard MOESSNER, Christiane NEUMANN
  • ANTI-HLA-G ANTIBODIES AND USE THEREOF
    Publication number: 20230159642
    Abstract: The present invention relates to antibodies that bind to human HLA-G, multispecific antibodies thereof, their preparation, formulations, and methods of using the same.
    Type: Application
    Filed: October 18, 2022
    Publication date: May 25, 2023
    Inventors: Alexander BUJOTZEK, Alejandro CARPY GUTIERREZ CIRLOS, Anne FREIMOSER-GRUNDSCHOBER, Carina HAGE, Thomas HOFER, Silke KIRCHNER, Meher MAJETY, Ekkehard MOESSNER, Christiane NEUMANN, Christian SPICK, Georg TIEFENTHALER, Thomas WEINDL
  • Anti-HLA-G antibodies and use thereof
    Publication number: 20220213199
    Abstract: The present invention relates antibodies that bind to human HLA-G, multispecific antibodies thereof, their preparation, formulations and methods of using the same.
    Type: Application
    Filed: December 15, 2021
    Publication date: July 7, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Alexander Bujotzek, Alejandro Carpy Gutierrez Cirlos, Anne Freimoser-Grundschober, Carina Hage, Thomas Hofer, Silke Kirchner, Meher Majety, Ekkehard Moessner, Christiane Neumann, Christian Spick, Georg Tiefenthaler, Thomas Weindl
  • ANTIBODIES BINDING TO CD3
    Publication number: 20220010015
    Abstract: The present invention generally relates to antibodies that bind to CD3, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
    Type: Application
    Filed: June 17, 2021
    Publication date: January 13, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Alejandro CARPY GUTIERREZ CIRLOS, Anne FREIMOSER-GRUNDSCHOBER, Thomas HOFER, Christian KLEIN, Ekkehard MOESSNER, Christiane NEUMANN, Pablo Umaña
  • Antibodies binding to HLA-A2/MAGE-A4
    Publication number: 20210230278
    Abstract: The present invention generally relates to antibodies that bind to HLA-A2/MAGE-A4, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
    Type: Application
    Filed: December 17, 2020
    Publication date: July 29, 2021
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Tina Weinzierl, Lydia Jasmin Hanisch, Alexander Bujotzek, Alejandro Carpy Gutierrez Cirlos, Stefan Klostermann, Christian Klein, Simon Patrick Keiser, Tanja Fauti, Estelle Marrer-Berger, Pablo Umaña