Abstract: Methods, systems, and computer storage media for providing drilling advisory recommendation using a drilling advisory engine in a material processing system that supports drilling operations. A drilling advisory recommendation identifies prescriptions (e.g., an arrangement of components and settings) in the material processing system to support real time optimization of drilling operations. The drilling advisory engine can be implemented as a real time prescriptive tool for operators (e.g., field personnel) to offer guidance for drilling operations. In operation, input data comprising real time sensor data of drilling operations, historical drilling information, and contextual drilling information associated with a drilling site are accessed. The input data is analyzed using two or more drilling advisory models that support generating drilling advisory recommendations that identify prescriptions for drilling operations.