Patents by Inventor Alejandro Gutierrez

Alejandro Gutierrez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260151467
    Abstract: Described herein are methods and compositions for treating cancer. Aspects of the invention relate to administering to a subject having cancer an asparaginase and an agent that inhibits GSK3?. Another aspect of the invention relates to administering an asparaginase to a subject having cancer that comprises an inactivating mutation in GSK3?.
    Type: Application
    Filed: August 4, 2025
    Publication date: June 4, 2026
    Applicant: THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Alejandro GUTIERREZ, Laura HINZE
  • Patent number: 12590966
    Abstract: Described herein are methods and compositions for treating cancer. Aspects of the invention relate to determining if a biological sample obtained from a subject for GSK3? bodies (puncta), e.g., in response to asparaginase treatment, and administering to a subject having cancer an asparaginase and an agent that inhibits GSK3? to a subject who has been identified as forming GSK3?-positive bodies.
    Type: Grant
    Filed: November 3, 2020
    Date of Patent: March 31, 2026
    Inventors: Alejandro Gutierrez, Laura Hinze
  • Publication number: 20250229506
    Abstract: The present invention contemplates a method for forming a composite structure including a plurality of rigid layers and one or more reformable epoxy resin layers. The resulting composite is molded to form a non-planar composite structure.
    Type: Application
    Filed: April 7, 2025
    Publication date: July 17, 2025
    Inventors: Sylvain Gleyal, Craig Chmielewski, Brandon Madaus, Alejandro Gutierrez
  • Patent number: 12280582
    Abstract: The present invention contemplates a method for forming a composite structure including a plurality of rigid layers and one or more reformable epoxy resin layers. The resulting composite is molded to form a non-planar composite structure.
    Type: Grant
    Filed: February 22, 2023
    Date of Patent: April 22, 2025
    Assignee: ZEPHYROS, INC
    Inventors: Sylvain Gleyal, Craig Chmielewski, Brandon Madaus, Alejandro Gutierrez
  • Patent number: 12034983
    Abstract: A method and system for controlling dynamic ad replacement. An example method involves a computing system detecting that first and second ad-replacement platforms are or will be in contention with each other for replacement of a replaceable ad in a media stream and, responsive to at least the detecting, the computing system (i) deciding that the first ad-replacement platform should replace the replaceable ad and that the second ad-replacement platform should not replace the replaceable ad, and (ii) based on the deciding, causing the first ad-replacement platform to replace the replaceable ad and the second ad-replacement platform to not replace the replaceable ad.
    Type: Grant
    Filed: February 9, 2022
    Date of Patent: July 9, 2024
    Assignee: Roku, Inc.
    Inventors: Brian P. Jentz, Alejandro Gutierrez, Stefanos C. Liassides
  • Publication number: 20240191942
    Abstract: Methods and apparatus for drying foodstuff such as nuts, fruits, and vegetables above ground with natural airflow that is typical during the drying season. The apparatus can be configured for placement with a container or integrated into the interior of a container, such as stationary containers, moveable containers, trailer containers, above-ground containers, and containers with sidewalls through which air can flow.
    Type: Application
    Filed: December 12, 2023
    Publication date: June 13, 2024
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Stefano Foresti, Alejandro Gutierrez
  • Publication number: 20240024436
    Abstract: Described herein are methods and compositions for treating cancer. Aspects of the invention relate to administering to a subject having cancer an asparaginase and an agent that inhibits G6PD. Another aspect of the invention relates to administering an asparaginase to a subject having cancer that comprises a G6PD deficiency.
    Type: Application
    Filed: June 7, 2023
    Publication date: January 25, 2024
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Yun-Cheol CHAE, Alejandro GUTIERREZ
  • Publication number: 20230211578
    Abstract: The present invention contemplates a method for forming a composite structure including a plurality of rigid layers and one or more reformable epoxy resin layers. The resulting composite is molded to form a non-planar composite structure.
    Type: Application
    Filed: February 22, 2023
    Publication date: July 6, 2023
    Inventors: Sylvain Gleyal, Craig Chmielewski, Brandon Madaus, Alejandro Gutierrez
  • Patent number: 11695972
    Abstract: A method and system to help control when to monitor for presence of replaceable advertisements in a media stream. An example method includes determining a time offset based at least on a difference between (i) a time of occurrence of a content event in a media stream as indicated by data carried in-band with the media stream and (ii) a time of occurrence of the content event in the media stream as indicated by schedule data that is not carried in-band with the media stream. Further, the method includes applying the determined time offset as a basis to adjust a scheduled time of an advertisement in the media stream, and using the adjusted scheduled time of the advertisement in the media stream as a basis to control when to monitor for presence of a replacement advertisement in the media stream.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: July 4, 2023
    Assignee: Roku, Inc.
    Inventors: Alejandro Gutierrez, John E. Sormark, Shashank C. Merchant, Brian P. Jentz, John L. Haynes, III
  • Publication number: 20230003732
    Abstract: Described herein are methods and compositions for treating cancer. Aspects of the invention relate to determining if a biological sample obtained from a subject for GSK3a bodies (puncta), e.g., in response to asparaginase treatment, and administering to a subject having cancer an asparaginase and an agent that inhibits GSK3? to a subject who has been identified as forming GSK3?-positive bodies.
    Type: Application
    Filed: November 3, 2020
    Publication date: January 5, 2023
    Applicant: THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Alejandro GUTIERREZ, Laura HINZE
  • Publication number: 20220264171
    Abstract: A method and system for harvesting ads or other modifiable-content segments for use to facilitate dynamic ad replacement or other dynamic content modification. An example method includes (i) determining, based on data carried in-band with a media stream being distributed, a time position of an ad in the media stream, (ii) using the determined time position of the ad in the media stream as a basis to select, from reference fingerprints representing the media stream, a set of the reference fingerprints that represent the ad in the media stream, and (iii) populating the selected set of reference fingerprints into an ad-inventory database as a set of fingerprints representing the ad, to facilitate later detecting presence of another instance of the same ad in the media stream or in another media stream and, based on the later detecting, dynamically replacing the detected other instance of the ad.
    Type: Application
    Filed: June 4, 2021
    Publication date: August 18, 2022
    Inventors: Alejandro Gutierrez, John E. Sormark, Shashank C. Merchant, Brian P. Jentz, John L. Haynes, III
  • Publication number: 20220264162
    Abstract: A method and system to help control when to monitor for presence of replaceable advertisements in a media stream. An example method includes determining a time offset based at least on a difference between (i) a time of occurrence of a content event in a media stream as indicated by data carried in-band with the media stream and (ii) a time of occurrence of the content event in the media stream as indicated by schedule data that is not carried in-band with the media stream. Further, the method includes applying the determined time offset as a basis to adjust a scheduled time of an advertisement in the media stream, and using the adjusted scheduled time of the advertisement in the media stream as a basis to control when to monitor for presence of a replacement advertisement in the media stream.
    Type: Application
    Filed: July 12, 2021
    Publication date: August 18, 2022
    Inventors: Alejandro Gutierrez, John E. Sormark, Shashank C. Merchant, Brian P. Jentz, John L. Haynes, III
  • Publication number: 20220264163
    Abstract: A method and system for controlling dynamic ad replacement. An example method involves a computing system detecting that first and second ad-replacement platforms are or will be in contention with each other for replacement of a replaceable ad in a media stream and, responsive to at least the detecting, the computing system (i) deciding that the first ad-replacement platform should replace the replaceable ad and that the second ad-replacement platform should not replace the replaceable ad, and (ii) based on the deciding, causing the first ad-replacement platform to replace the replaceable ad and the second ad-replacement platform to not replace the replaceable ad.
    Type: Application
    Filed: February 9, 2022
    Publication date: August 18, 2022
    Inventors: Brian P. Jentz, Alejandro Gutierrez, Stefanos C. Liassides
  • Publication number: 20210299233
    Abstract: Described herein are methods and compositions for treating cancer. Aspects of the invention relate to administering to a subject having cancer an asparaginase and an agent that inhibits GSK3f. Another aspect of the invention relates to administering an asparaginase to a subject having cancer that comprises an inactivating mutation in GSK3f.
    Type: Application
    Filed: June 12, 2019
    Publication date: September 30, 2021
    Applicant: THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Alejandro GUTIERREZ, Laura HINZE
  • Publication number: 20190378161
    Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to integrate tagged media impressions with panelist information. An example apparatus includes: a memory; and a processor to: request a unique identifier of a panelist from a central server in an audience measurement environment; receive the unique identifier of the panelist; and modify a user agent setting of a web browser executing on the processor to insert the unique identifier of the panelist into a user agent string of the web browser.
    Type: Application
    Filed: June 11, 2018
    Publication date: December 12, 2019
    Inventor: Alejandro Gutierrez
  • Patent number: 10436760
    Abstract: The invention relates to a humidity indicating composition comprising (a) an organic pH indicator dye compound, (b) a Bronsted base comprising an organosilane, (c) a moisture-curable binder, (d) an optional rheology additive and (e) an optional alkaline filler.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: October 8, 2019
    Assignee: BELISARIUS B.V.
    Inventors: Sander Van Loon, Alejandro Gutierrez, Gwenola Le Mouée, Marco Verschuur
  • Patent number: 9769294
    Abstract: Methods, apparatus, systems and articles of manufacture to monitor mobile devices are disclosed. An example apparatus includes a shell having a form factor dimensioned to receive a mobile device; and a near-field interceptor coupled to the shell, the near-field interceptor to capture data communicated via a near-field energy field between a first near-field communication device of the mobile device and a second near field communication device external to the mobile device.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: September 19, 2017
    Assignee: The Nielsen Company (US), LLC
    Inventor: Alejandro Gutierrez
  • Publication number: 20170160247
    Abstract: The invention relates to a humidity indicating composition comprising (a) an organic pH indicator dye compound, (b) a Bronsted base comprising an organosilane, (c) a moisture-curable binder, (d) an optional rheology additive and (e) an optional alkaline filler.
    Type: Application
    Filed: December 2, 2016
    Publication date: June 8, 2017
    Inventors: Sander VAN LOON, Alejandro GUTIERREZ, Gwenola LE MOUÉE, Marco VERSCHUUR
  • Publication number: 20160212250
    Abstract: Methods, apparatus, systems and articles of manufacture to monitor mobile devices are disclosed. An example apparatus includes a shell having a form factor dimensioned to receive a mobile device; and a near-field interceptor coupled to the shell, the near-field interceptor to capture data communicated via a near-field energy field between a first near-field communication device of the mobile device and a second near field communication device external to the mobile device.
    Type: Application
    Filed: March 30, 2016
    Publication date: July 21, 2016
    Inventor: Alejandro Gutierrez
  • Patent number: 9325381
    Abstract: Methods, apparatus, systems and articles of manufacture to monitor mobile devices are disclosed. An example apparatus includes a shell having a form factor dimensioned to receive a mobile device; and a near-field interceptor coupled to the shell, the near-field interceptor to capture data communicated via a near-field energy field between a first near-field communication device of the mobile device and a second near field communication device external to the mobile device.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: April 26, 2016
    Assignee: The Nielsen Company (US), LLC
    Inventor: Alejandro Gutierrez