Patents by Inventor Alejandro Hernandez
Alejandro Hernandez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250082747Abstract: The present invention relates to a vaccine for protecting a pig against diseases associated with corona virus infection including porcine epidemic diarrhea virus (PEDV) and/or porcine deltacorona virus (PDCoV). The vaccine commonly includes inactivated/killed PEDV (e.g., chemically inactivated PED virus), and/or recombinant PEDV antigen, and/or an adjuvant inactivated/killed PDCoV (e.g., chemically inactivated PDCoV virus), and/or recombinant PDCoV antigen and an adjuvant. Methods for protecting pigs against diseases associated with PEDV and/or PDCoV and methods of producing the porcine epidemic diarrhea virus and/or porcine deltacorona virus vaccine are also provided.Type: ApplicationFiled: September 23, 2024Publication date: March 13, 2025Inventors: Scott ACKERMAN, Joseph Ralph HERMANN, Luis Alejandro HERNANDEZ, Lea Ann HOBBS, Arun V. IYER, Sean O'CONNER, Abby Rae PATTERSON, Eric Martin VAUGHN, Joseph Gilbert VICTORIA
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Patent number: 12247051Abstract: Vaccination methods to control PCV2 infection with different PCV2 subtypes are disclosed. Specifically, a PCV2 subtype b (PCV2b) ORF2 proteins or immunogenic compositions comprising a PCV2b ORF2 protein are used in a method for the treatment or prevention of an infection with PCV2 of the same PCV2b and/or different subtype; the reduction, prevention or treatment of clinical signs caused by an infection with PCV2 of the same PCV2b or a different subtype; and/or the prevention or treatment of a disease caused by an infection with PCV2 of the same PCV2b and/or a different subtype. The present invention in particular relates to PCV2 subtype b (PCV2b) ORF2 proteins characterized in that they contain at least one mutation in the BC loop that such that the expressed protein is preferably expressed in a higher amount compared to a PCV2 ORF2 protein that does not contain such mutation.Type: GrantFiled: November 21, 2023Date of Patent: March 11, 2025Inventors: Luis Alejandro Hernandez, Christine Margaret Muehlenthaler, Eric Martin Vaughn, Gregory Haiwick
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Patent number: 12235851Abstract: Methods for operation fragmentation with metadata serialization in query processing pushdowns are performed by systems and devices. A compute node receives a query directed to database data, and generates query text fragments. Portions of metadata of the database are read from different page servers, and are serialized by the compute node. Page identities of data pages in a page server that stores the data are determined from a page index at the compute node, and the compute node provides the text fragments, the serialized metadata, and the page identities to the page server storing the data. The page server compiles the text fragments based on the serialized metadata to generate an executable query plan for the query. The page server initializes and performs execution of the executable query plan against the data as a pushdown query operation, and a result of pushdown query operation is provided to the compute node.Type: GrantFiled: September 26, 2022Date of Patent: February 25, 2025Assignee: MICROSOFT TECHNOLOGY LICENSING, LLCInventors: Craig S. Freedman, Adrian-Leonard Radu, Daniel G. Schall, Hanumantha R. Kodavalla, Panagiotis Antonopoulos, Raghavendra Thallam Kodandaramaih, Alejandro Hernandez Saenz, Naveen Prakash
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Patent number: 12210514Abstract: Distributed database systems including compute nodes and page servers are described herein that enable compute nodes to pushdown certain query processing compute tasks to the page servers to take advantage of otherwise idle compute resources at the page servers, and to reduce the quantity of data that moves between compute nodes and page servers. A distributed database system includes a page server and a compute node, wherein the page server is configured to maintain multiple versions of stored data objects. The compute node is configured to receive a query and generate a transaction context (TC) and modified table schemas (MTS) scoped to the query, and pushdown the query, TC and MTS to the page server that is configured to determine which data objects at the page server satisfy the query, and for each such object, which version of the object should be returned based on the TC.Type: GrantFiled: July 31, 2023Date of Patent: January 28, 2025Assignee: MICROSOFT TECHNOLOGY LICENSING, LLCInventors: Craig S. Freedman, Adrian-Leonard Radu, Daniel G. Schall, Hanumantha R. Kodavalla, Panagiotis Antonopoulos, Raghavendra Thallam Kodandaramaih, Alejandro Hernandez Saenz, Naveen Prakash
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Publication number: 20240427792Abstract: Distributed database systems including compute nodes and page servers are described herein that enable separating logical and physical storage of database files in a distributed database system. A distributed database system includes a page server and a compute node, and is configured to store a logical database file that includes data and is associated with a file identifier. Each page server is configurable to store slices (i.e., subportions) of the logical database file. The compute node is coupled to the plurality of page servers and configured to store the logical database file responsive to a received command. In an aspect, such storage may comprise slicing the data comprising the logical database file into a set of slices with each being associated with a respective page server, maintaining an endpoint mapping for each slice of the first set of slices, and transmitting each slice to the associated for storage thereby.Type: ApplicationFiled: September 5, 2024Publication date: December 26, 2024Inventors: Alejandro Hernandez SAENZ, Cristian DIACONU, Krystyna Ewa REISTETER, Naveen PRAKASH, Sheetal SHROTRI, Rogério RAMOS, Alexander BUDOVSKI, Hanumantha Rao KODAVALLA
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Patent number: 12150983Abstract: The present invention relates to a vaccine for protecting a pig against diseases associated with corona virus infection including porcine epidemic diarrhea virus (PEDV) and/or porcine deltacorona virus (PDCoV). The vaccine commonly includes inactivated/killed PEDV (e.g., chemically inactivated PED virus), and/or recombinant PEDV antigen, and/or an adjuvant inactivated/killed PDCoV (e.g., chemically inactivated PDCoV virus), and/or recombinant PDCoV antigen and an adjuvant. Methods for protecting pigs against diseases associated with PEDV and/or PDCoV and methods of producing the porcine epidemic diarrhea virus and/or porcine deltacorona virus vaccine are also provided.Type: GrantFiled: January 26, 2018Date of Patent: November 26, 2024Inventors: Scott Ackerman, Joseph Ralph Hermann, Luis Alejandro Hernandez, Lea Ann Hobbs, Arun V. Iyer, Sean O'Conner, Abby Rea Patterson, Eric Martin Vaughn, Joseph Gilbert Victoria
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Patent number: 12118014Abstract: Distributed database systems including compute nodes and page servers are described herein that enable separating logical and physical storage of database files in a distributed database system. A distributed database system includes a page server and a compute node, and is configured to store a logical database file that includes data and is associated with a file identifier. Each page server is configurable to store slices (i.e., subportions) of the logical database file. The compute node is coupled to the plurality of page servers and configured to store the logical database file responsive to a received command. In an aspect, such storage may comprise slicing the data comprising the logical database file into a set of slices with each being associated with a respective page server, maintaining an endpoint mapping for each slice of the first set of slices, and transmitting each slice to the associated for storage thereby.Type: GrantFiled: July 12, 2023Date of Patent: October 15, 2024Assignee: MICROSOFT TECHNOLOGY LICENSING, LLCInventors: Alejandro Hernandez Saenz, Cristian Diaconu, Krystyna Ewa Reisteter, Naveen Prakash, Sheetal Shrotri, Rogério Ramos, Alexander Budovski, Hanumantha Rao Kodavalla
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Publication number: 20240286280Abstract: A method of controlling an actuator having a maximum velocity and a maximum acceleration includes accessing a reference trajectory signal comprising temporally-spaced reference positions for the actuator and accessing a trajectory template having at least a third derivative continuity and at least one characteristic constrained by the maximum velocity and the maximum acceleration. The method includes generating a smooth reference trajectory signal based on the reference trajectory signal and the trajectory template and outputting the smooth reference trajectory signal. Controls for the actuator can be generated based on the smooth reference trajectory signal.Type: ApplicationFiled: February 5, 2024Publication date: August 29, 2024Inventors: Peyman Karimi Eskandary, Alejandro Hernandez Herdocia
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Publication number: 20240226264Abstract: The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 3 (PCV3) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV3 infection.Type: ApplicationFiled: December 27, 2023Publication date: July 11, 2024Inventors: Arun IYER, Luis Alejandro Hernandez, Abby Patterson, Bailey Arruda, Luis Gabriel Gimenez-Lirola, Dave Michael Anstrom, Eric M. Vaughn, Pablo E Pineyro Pineiro, Troy James Kaiser, Joseph Ralph Hermann
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Patent number: 11966511Abstract: For measuring quality of view over a visual field of view of an eye, during a measuring period, deviations between gaze positions and associated stimulus positions where the stimulus to be followed was displayed when the gaze position was detected and magnitudes of the registered deviations arte determined. For each field portion of a map of a visual field of view, quality of view is determined in accordance with a quality of view estimates of associated ones of the registered deviations of which the associated stimulus positions are located relative to the gaze position so that the associated stimulus positions are in that field portion. For each of the associated ones of the registered deviations, the quality of view is estimated in accordance with the magnitude of that associated one of the registered deviations and with magnitudes of at least preceding or succeeding ones of the registered deviations.Type: GrantFiled: November 13, 2020Date of Patent: April 23, 2024Assignees: Rijksuniversiteit Groningen, Academisch Ziekenhuis GroningenInventors: Alessandro Grillini, Alejandro Hernández Garcia, Remco Jan Renken
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Publication number: 20240126706Abstract: Methods for local page writes via pre-staging buffers for resilient buffer pool extensions are performed by computing systems. Compute nodes in database systems insert, update, and query data pages maintained in storage nodes. Data pages cached locally by compute node buffer pools are provided to buffer pool extensions on local disks as pre-copies via staging buffers that store data pages prior to local disk storage. Encryption of data pages occurs at the staging buffers, which allows a less restrictive update latching during the copy process, with page metadata being updated in buffer pool extensions page tables with in-progress states indicating it is not yet written to local disk. When stage buffers are filled, data pages are written to buffer pool extensions and metadata is updated in page tables to indicate available/valid states. Data pages in staging buffers can be read and updated prior to writing to the local disk.Type: ApplicationFiled: December 8, 2023Publication date: April 18, 2024Inventors: Rogério RAMOS, Kareem Aladdin GOLAUB, Chaitanya GOTTIPATI, Alejandro Hernandez SAENZ, Raj Kripal DANDAY
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Patent number: 11942839Abstract: The present disclosure relates to methods and tools for mounting and/or removing active parts of a stator of an electrical machine, e.g. a generator. The present disclosure also relates to rotors, stators and generators. A method comprises removing one or more active rotor parts of a rotor of an electrical machine when the rotor is in a removal starting position, arranging a replacement tool in a gap left by the removed active rotor parts, rotating the rotor to an alignment position such that the replacement tool is radially aligned with an active stator part to be removed, picking the active stator part to be removed with the replacement tool, rotating the rotor to an extraction position, and removing the active stator part from the rotor.Type: GrantFiled: May 27, 2022Date of Patent: March 26, 2024Assignee: General Electric Renovables Espana, S.L.Inventors: Alejandro Hernandez Ferre, Pablo Pozo Torres
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Publication number: 20240076321Abstract: Vaccination methods to control PCV2 infection with different PCV2 subtypes are disclosed. Specifically, a PCV2 subtype b (PCV2b) ORF2 proteins or immunogenic compositions comprising a PCV2b ORF2 protein are used in a method for the treatment or prevention of an infection with PCV2 of the same PCV2b and/or different subtype; the reduction, prevention or treatment of clinical signs caused by an infection with PCV2 of the same PCV2b or a different subtype; and/or the prevention or treatment of a disease caused by an infection with PCV2 of the same PCV2b and/or a different subtype. The present invention in particular relates to PCV2 subtype b (PCV2b) ORF2 proteins characterized in that they contain at least one mutation in the BC loop that such that the expressed protein is preferably expressed in a higher amount compared to a PCV2 ORF2 protein that does not contain such mutation.Type: ApplicationFiled: November 21, 2023Publication date: March 7, 2024Inventors: Luis Alejandro HERNANDEZ, Christine Margaret MUEHLENTHALER, Eric Martin VAUGHN, Gregory HAIWICK
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Patent number: 11896659Abstract: The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 3 (PCV3) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV3 infection.Type: GrantFiled: November 23, 2022Date of Patent: February 13, 2024Inventors: Arun Iyer, Luis Alejandro Hernandez, Abby Patterson, Bailey Arruda, Luis Gabriel Gimenez-Lirola, Dave Michael Anstrom, Eric M. Vaughn, Pablo E Pineyro Pineiro, Troy James Kaiser, Joseph Ralph Hermann
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Patent number: 11880318Abstract: Methods for local page writes via pre-staging buffers for resilient buffer pool extensions are performed by computing systems. Compute nodes in database systems insert, update, and query data pages maintained in storage nodes. Data pages cached locally by compute node buffer pools are provided to buffer pool extensions on local disks as pre-copies via staging buffers that store data pages prior to local disk storage. Encryption of data pages occurs at the staging buffers, which allows a less restrictive update latching during the copy process, with page metadata being updated in buffer pool extensions page tables with in-progress states indicating it is not yet written to local disk. When stage buffers are filled, data pages are written to buffer pool extensions and metadata is updated in page tables to indicate available/valid states. Data pages in staging buffers can be read and updated prior to writing to the local disk.Type: GrantFiled: March 28, 2022Date of Patent: January 23, 2024Assignee: MICROSOFT TECHNOLOGY LICENSING, LLCInventors: Rogério Ramos, Kareem Aladdin Golaub, Chaitanya Gottipati, Alejandro Hernandez Saenz, Raj Kripal Danday
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Patent number: 11860829Abstract: Methods for page split detection and affinity in query processing pushdowns are performed by systems and devices. Page servers perform pushdown operations based on specific, and specifically formatted or generated, information, instructions, and data provided thereto from a compute node. Page servers also determine that page splits have occurred during reading of data pages maintained by page servers during pushdown operations, and also during fulfillment of compute node data requests. To detect a data page has split, page servers utilize information from a compute node of an expected next data page which is compared to a next data page in the page server page index. A mismatch in the comparison by page servers indicates data page was split. Compute nodes and page servers store and maintain off-row data generated during data operations via page affinity considerations where the off-row data is stored at the same page server as the data.Type: GrantFiled: February 19, 2021Date of Patent: January 2, 2024Assignee: MICROSOFT TECHNOLOGY LICENSING, LLCInventors: Craig S. Freedman, Adrian-Leonard Radu, Daniel G. Schall, Hanumantha R. Kodavalla, Panagiotis Antonopoulos, Raghavendra Thallam Kodandaramaih, Alejandro Hernandez Saenz, Naveen Prakash
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Patent number: 11858963Abstract: Vaccination methods to control PCV2 infection with different PCV2 subtypes are disclosed. Specifically, a PCV2 subtype b (PCV2b) ORF2 proteins or immunogenic compositions comprising a PCV2b ORF2 protein are used in a method for the treatment or prevention of an infection with PCV2 of the same PCV2b and/or different subtype; the reduction, prevention or treatment of clinical signs caused by an infection with PCV2 of the same PCV2b or a different subtype; and/or the prevention or treatment of a disease caused by an infection with PCV2 of the same PCV2b and/or a different subtype. The present invention in particular relates to PCV2 subtype b (PCV2b) ORF2 proteins characterized in that they contain at least one mutation in the BC loop that such that the expressed protein is preferably expressed in a higher amount compared to a PCV2 ORF2 protein that does not contain such mutation.Type: GrantFiled: March 29, 2021Date of Patent: January 2, 2024Inventors: Luis Alejandro Hernandez, Christine Margaret Muehlenthaler, Eric Martin Vaughn, Gregory Haiwick
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Patent number: 11851012Abstract: An automotive busbar includes a first rigid section and a second rigid section, each of the first and second rigid sections formed from a first conductive metallic material and having a first effective cross-sectional area, and a flexible section positioned between and interconnecting the first and second rigid sections, the flexible section made from a second conductive metallic material and having a second effective cross sectional area, and a top surface and a bottom surface, at least one of the top and bottom surface including a plurality of voids formed therein and spaced along the flexible section, wherein, the second effective cross-sectional area is less than the first effective cross-sectional area and the second conductive material has a higher conductivity than the first conductive material.Type: GrantFiled: April 9, 2021Date of Patent: December 26, 2023Assignee: GM GLOBAL TECHNOLOGY OPERATIONS LLCInventors: Alejandro Hernandez Covarrubias, Francisco David Velasco, Manuel Garduno
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Patent number: 11835027Abstract: The present disclosure relates to supporting structures for a central frame of a direct-drive wind turbine and methods for managing such structures. A supporting structure is configured to assume a deployed configuration and a stowed configuration. In the stowed configuration, the supporting structure has a shape and size such that the supporting structure can be introduced into the central frame from an outside. In the deployed configuration, the supporting structure has one or more increased dimensions with respect to the stowed configuration, and comprises a working platform.Type: GrantFiled: June 7, 2022Date of Patent: December 5, 2023Assignee: General Electric Renovables Espana, S.L.Inventor: Alejandro Hernandez Ferre
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Patent number: D1073796Type: GrantFiled: July 5, 2022Date of Patent: May 6, 2025Assignee: Apple Inc.Inventors: Taylor Hoff, Alejandro Hernandez Torres, Haiden Goggin, Kameron Gad, Stephen Yustiono