Patents by Inventor Alejandro Monteys

Alejandro Monteys has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR INDUCIBLE ALTERNATIVE SPLICING REGULATION OF GENE EXPRESSION
    Publication number: 20250303000
    Abstract: Provided herein are chimeric minigenes, where the alternative splicing of the minigene determines whether an encoded gene is expressed. In particular, the minigenes are alternatively spliced in response to splicing modulator drugs, such that the encoded gene is only expressed in the present of the splicing modulator drug. The encoded gene may encode an inhibitory RNA, a CRISPR-Cas9 protein, a transactivator, or a therapeutic protein.
    Type: Application
    Filed: May 18, 2023
    Publication date: October 2, 2025
    Applicant: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
    Inventors: Beverly DAVIDSON, Alejandro MONTEYS
  • Compositions and methods for treating fragile X syndrome and related syndromes
    Patent number: 11497816
    Abstract: Compositions and methods are provided for the inhibition, treatment and/or prevention of fragile X syndrome and related disorders.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: November 15, 2022
    Assignee: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
    Inventors: Beverly L. Davidson, Carolyn M. Yrigollen, Alejandro Monteys, Bryan Simpson
  • Compositions and Methods for Treating Fragile X Syndrome and Related Syndromes
    Publication number: 20180296698
    Abstract: Compositions and methods are provided for the inhibition, treatment and/or prevention of fragile X syndrome and related disorders.
    Type: Application
    Filed: October 6, 2016
    Publication date: October 18, 2018
    Inventors: Beverly L. Davidson, Carolyn M. Yrigollen, Alejandro Monteys, Bryan Simpson