Abstract: Embodiments include example systems, methods, and computer-accessible mediums for analysis and visualization of data associated with anatomical images. In some embodiments the anatomical images can be spinal images used for assessment of stenosis and disc degeneration. In some embodiments, systems, devices, and methods described herein include selecting a region of interest (ROI) in a three-dimensional (3D) volume of image data of a plurality of vertebra of a spine, identifying one or more anatomical parts in the ROI, determining one or more parameters of the one or more anatomical parts, and assessing a severity of a spinal deformity based on the one or more parameters.