Patents by Inventor Alejandro TOCIGL
Alejandro TOCIGL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260183766Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods that may be used to safely manually add or remove fluid within a cartridge while it is actively applying DMF. Also described herein are DMF readers for use with a DMF cartridges, including those including multiple and/or redundant safety interlocks. Also described herein are DMF reader devices having a cover with active control of microfluidics on the cover while actively controlling DMF on the reader base.Type: ApplicationFiled: February 20, 2026Publication date: July 2, 2026Inventors: Jorge Abraham SOTO-MORENO, Mais Jehan JEBRAIL, Alejandro TOCIGL, Foteini CHRISTODOULOU, Carl David MARTIN, Morgan Marin WATSON, Rohit LAL, Joshua SHEN, Ronan Barry HAYES, Gregory Arthur RAY, Peter Tirtowijoyo YOUNG, Spencer Todd SEILER, Ik Pyo HONG, Mohan GURUNATHAN, Lubomir DALTCHEV, Rodolfo WILHELMY-PRECIADO, Juan Matias DeCARLI, Jobelo Andres Quintero RODRÍGUEZ, Matias Jorge LESCANO
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Patent number: 12582991Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods that may be used to safely manually add or remove fluid within a cartridge while it is actively applying DMF. Also described herein are DMF readers for use with a DMF cartridges, including those including multiple and/or redundant safety interlocks. Also described herein are DMF reader devices having a cover with active control of microfluidics on the cover while actively controlling DMF on the reader base.Type: GrantFiled: February 28, 2020Date of Patent: March 24, 2026Assignee: INTEGRA Biosciences AGInventors: Jorge Abraham Soto-Moreno, Mais Jehan Jebrail, Alejandro Tocigl, Foteini Christodoulou, Carl David Martin, Morgan Marin Watson, Rohit Lal, Joshua Shen, Ronan Barry Hayes, Gregory Arthur Ray, Peter Tirtowijoyo Young, Spencer Todd Seiler, Ik Pyo Hong, Mohan Gurunathan, Lubomir Daltchev, Rodolfo Wilhelmy-Preciado, Juan Matias de Carli, Jobelo Andres Quintero Rodríguez, Matias Jorge Lescano
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Publication number: 20260070060Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.Type: ApplicationFiled: November 13, 2025Publication date: March 12, 2026Inventors: Jorge Abraham SOTO-MORENO, Ik Pyo HONG, Jair Giovanny BELTRAN-VERA, Juan Matias DeCARLI, Jobelo Andres Quintero RODRIGUEZ, Rodolfo WILHELMY-PRECIADO, Mais Jehan JEBRAIL, Gregory RAY, Mathieu Gabriel-Emmanuel CHAULEAU, Paul Mathew LUNDQUIST, Alejandro TOCIGL, John Peter CANNISTRARO, Gareth SCOTT, Spencer SEILER, Rohit LAL, Eugenia CARVAJAL, Eduardo CERVANTES, Nikolay SERGEEV, Yu-Hung CHEN, Poornasree KUMAR, Foteini CHRISTODOULOU
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Patent number: 12515225Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.Type: GrantFiled: April 25, 2022Date of Patent: January 6, 2026Assignee: INTEGRA Biosciences AGInventors: Jorge Abraham Soto-Moreno, Ik Pyo Hong, Jair Giovanny Beltran-Vera, Juan Matias DeCarli, Jobelo Andres Quintero Rodriguez, Rodolfo Wilhelmy-Preciado, Mais Jehan Jebrail, Gregory Ray, Mathieu Gabriel-Emmanuel Chauleau, Paul Mathew Lundquist, Alejandro Tocigl, John Peter Cannistraro, Gareth Scott, Spencer Seiler, Rohit Lal, Eugenia Carvajal, Eduardo Cervantes, Nikolay Sergeev, Yu-Hung Chen, Poornasree Kumar, Foteini Christodoulou
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Publication number: 20220250078Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.Type: ApplicationFiled: April 25, 2022Publication date: August 11, 2022Inventors: Jorge Abraham SOTO-MORENO, Ik Pyo HONG, Jair Giovanny BELTRAN-VERA, Juan Matias DeCARLI, Jobelo Andres Quintero RODRIGUEZ, Rodolfo WILHELMY-PRECIADO, Mais Jehan JEBRAIL, Gregory RAY, Mathieu Gabriel-Emmanuel CHAULEAU, Paul Mathew LUNDQUIST, Alejandro TOCIGL, John Peter CANNISTRARO, Gareth SCOTT, Spencer SEILER, Rohit LAL, Eugenia CARVAJAL, Eduardo CERVANTES, Nikolay SERGEEV, Yu-Hung CHEN, Poornasree KUMAR, Foteini CHRISTODOULOU
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Publication number: 20220219172Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods that may be used to safely manually add or remove fluid within a cartridge while it is actively applying DMF. Also described herein are DMF readers for use with a DMF cartridges, including those including multiple and/or redundant safety interlocks. Also described herein are DMF reader devices having a cover with active control of microfluidics on the cover while actively controlling DMF on the reader base.Type: ApplicationFiled: February 28, 2020Publication date: July 14, 2022Applicant: MIROCULUS INC.Inventors: Jorge Abraham SOTO-MORENO, Mais Jehan JEBRAIL, Alejandro TOCIGL, Foteini CHRISTODOULOU, Carl David MARTIN, Morgan Marin WATSON, Rohit LAL, Joshua SHEN, Ronan Barry HAYES, Gregory Arthur RAY, Peter Tirtowijoyo YOUNG, Spencer Todd SEILER, Ik Pyo HONG, Mohan GURUNATHAN, Lubomir DALTCHEV, Rodolfo WILHELMY-PRECIADO, Juan Matias de CARLI, Jobelo Andres Quintero RODRÍGUEZ, Matias Jorge LESCANO
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Patent number: 11311882Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.Type: GrantFiled: January 28, 2019Date of Patent: April 26, 2022Assignee: mirOculus Inc.Inventors: Jorge Abraham Soto-Moreno, Ik Pyo Hong, Jair Giovanny Beltran-Vera, Juan Matias DeCarli, Jobelo Andres Quintero Rodriguez, Rodolfo Wilhelmy-Preciado, Mais Jehan Jebrail, Gregory Ray, Mathieu Gabriel-Emmanuel Chauleau, Paul Mathew Lundquist, Alejandro Tocigl, John Peter Cannistraro, Gareth Scott, Spencer Seiler, Rohit Lal, Eugenia Carvajal, Eduardo Cervantes, Nikolay Sergeev, Yu-Hung Chen, Poornasree Kumar, Foteini Christodoulou
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Publication number: 20190168223Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.Type: ApplicationFiled: January 28, 2019Publication date: June 6, 2019Inventors: Jorge Abraham SOTO-MORENO, Ik Pyo HONG, Jair Giovanny BELTRAN-VERA, Juan Matias DeCARLI, Jobelo Andres QUINTERO, Rodolfo WILHELMY-PRECIADO, Mais Jehan JEBRAIL, Gregory RAY, Mathieu Gabriel-Emmanuel CHAULEAU, Paul Mathew LUNDQUIST, Alejandro TOCIGL, John Peter CANNISTRARO, Gareth SCOTT, Spencer SEILER, Rohit LAL, Eugenia CARVAJAL, Eduardo CERVANTES, Nikolay SERGEEV, Yu-Hung CHEN, Poornasree KUMAR, Foteini CHRISTODOULOU
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Publication number: 20160319354Abstract: Methods and apparatuses for detecting microRNA from a tissue sample. In particular, described herein are multiplexed methods and apparatuses for implementing them for rapid and parallel detection of a profile of different microRNAs in a patient sample using a modified loop-mediated isothermal amplification (“LAMP”) technique.Type: ApplicationFiled: December 30, 2014Publication date: November 3, 2016Applicant: MIROCULUS INC.Inventors: Alejandro TOCIGL, Foteini CHRISTODOULOU, Pablo OLIVARES, Ferran GALINDO, Jorge SOTO