Patents by Inventor Aleksandar Francki
Aleksandar Francki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180298328Abstract: Provided herein are stimulated placental stem cells and methods of treating individuals having diseases or disorders of the circulatory system using stimulated placental cells. The invention also provides methods of inducing angiogenesis using such stimulated cells or populations of cells comprising such stimulated cells.Type: ApplicationFiled: May 25, 2016Publication date: October 18, 2018Applicant: Celularity, Inc.Inventors: Kathy E. KARASIEWICZ-MENDEZ, Aleksandar FRANCKI, Jeffrey TURNER, Eric LAW, Jennifer PAREDES, Kristen LABAZZO, Hemlata RANA, Wolfgang HOFGARTNER, Robert J. HARIRI
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Publication number: 20170252379Abstract: Provided herein are compositions of placenta-derived adherent cell exosomes and methods of making and using the same. In one aspect, provided herein are compositions comprising exosomes produced by and/or derived from placental cells, e.g., placenta-derived adherent cells. In certain embodiments, the exosomes provided herein are produced by placenta-derived adherent cells that have been cultured in vitro for, e.g., 1, 2, 3, 4, 5, 6 or more passages.Type: ApplicationFiled: October 8, 2015Publication date: September 7, 2017Applicant: Anthrogenesis CorporationInventors: Eric LAW, Andrew MORSCHAUSER, Aleksandar FRANCKI, Jennifer PAREDES, Kathy E. KARASIEWICZ-MENDEZ, Allan REDUTA, Vladimir JANKOVIC, Ivana DJURETIC
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Patent number: 9745554Abstract: The invention relates to the discovery that the proliferation and survival of pancreatic progenitor cells can be enhanced by contacting the cells with, (1) a caspase inhibitor sufficient to reduce apoptosis in the pancreatic endocrine cells; and, (2) a growth factor in an amount sufficient to increase the level of activated Akt in the pancreatic endocrine cells.Type: GrantFiled: January 18, 2007Date of Patent: August 29, 2017Assignee: ReNeuron, Inc.Inventors: Monica Florio, Aleksandar Francki, Wen-Ghih Tsang
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Publication number: 20160361366Abstract: Provided herein are novel angiogenic cells from amnion, referred to as amnion derived adherent cells, and populations of, and compositions comprising, such cells. Further provided herein are methods of obtaining such cells and methods of using the cells in the treatment of individuals.Type: ApplicationFiled: October 22, 2015Publication date: December 15, 2016Applicant: ANTHROGENESIS CORPORATIONInventors: Stewart Abbot, James W. Edinger, Aleksandar Francki, Aleksandr Kaplunovsky, Vladimir Jankovic, Kristen Labazzo, Eric Law, Neerav Padliya, Jennifer Paredes, Jia-Lun Wang
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Publication number: 20160106784Abstract: Provided herein are methods of treating individuals having diseases or disorders of the circulatory system, using placental cells, e.g., the placental stem cells and placental multipotent cells (PDACs) described herein, and populations of such placental cells. The invention also provides methods of angiogenesis using such cells or populations of cells comprising such cells.Type: ApplicationFiled: December 22, 2015Publication date: April 21, 2016Applicant: ANTHROGENESIS CORPORATIONInventors: Stewart Abbot, James W. Edinger, Aleksandar Francki, Robert J. Hariri, Vladimir Jankovic, Aleksandr Kaplunovsky, Kristen Labazzo, Eric Law, Neerav D. Padliya, Jennifer Paredes, Jia-Lun Wang
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Patent number: 9254302Abstract: Provided herein are methods of treating individuals having diseases or disorders of the circulatory system, using placental cells, e.g., the placental stem cells and placental multipotent cells (PDACs) described herein, and populations of such placental cells. The invention also provides methods of angiogenesis using such cells or populations of cells comprising such cells.Type: GrantFiled: April 6, 2011Date of Patent: February 9, 2016Assignee: ANTHROGENESIS CORPORATIONInventors: Stewart Abbot, James W. Edinger, Aleksandar Francki, Robert J. Hariri, Vladimir Jankovic, Aleksandr Kaplunovsky, Kristen Labazzo, Eric Law, Neerav D. Padliya, Jennifer Paredes, Jia-Lun Wang
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Patent number: 9198938Abstract: Provided herein are novel angiogenic cells from amnion, referred to as amnion derived adherent cells, and populations of, and compositions comprising, such cells. Further provided herein are methods of obtaining such cells and methods of using the cells in the treatment of individuals.Type: GrantFiled: December 26, 2012Date of Patent: December 1, 2015Assignee: ANTRHOGENESIS CORPORATIONInventors: Stewart Abbot, James W. Edinger, Aleksandar Francki, Aleksandr Kaplunovsky, Vladimir Jankovic, Kristen Labazzo, Eric Law, Neerav Padliya, Jennifer Paredes, Jia-Lun Wang
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Publication number: 20150023926Abstract: Provided herein are methods of treating individuals having suffered exposure to radiation, e.g., individuals having radiation injury, by administering to the individuals angiogenic cells from amnion, referred to as amnion derived adherent cells, or populations of and compositions comprising, such cells.Type: ApplicationFiled: July 13, 2012Publication date: January 22, 2015Applicant: ANTHROGENESIS CORPORATIONInventors: Aleksandar Francki, Ajai Pal, Robert J. Hariri, Vladimir Jankovic
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Publication number: 20140219970Abstract: Provided herein are compositions and methods of treating individuals having sarcoidosis or a sarcoidosis-related disease or disorder, using placental cells, e.g., the placental stem cells and placental multipotent cells (PDACs) described herein. Also provided herein are kits comprising said cells or a composition thereof.Type: ApplicationFiled: September 16, 2013Publication date: August 7, 2014Applicant: Anthrogenesis CorporationInventors: James W. Edinger, Steven Alan Fischkoff, Aleksandar Francki, Vladimir Jankovic, Bitao Liang, Philippe Martin, Cynthia Ray, Xiaockui Zhang
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Publication number: 20140072538Abstract: Provided herein are methods of treating individuals having suffered exposure to radiation, e.g., individuals having radiation injury, by administering to the individuals angiogenic cells from amnion, referred to as amnion derived adherent cells, or populations of, and compositions comprising, such cells.Type: ApplicationFiled: July 12, 2013Publication date: March 13, 2014Inventors: Aleksandar Francki, Ajai Pal, Robert J. Hariri, Vladimir Jankovic
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Patent number: 8562973Abstract: Methods of treating individuals having sarcoidosis or a sarcoidosis-related disease or disorder using placental cells are described. Also describe are kits comprising placental stem cells or a composition thereof that can be used in methods of treating sarcoidosis or a sarcoidosis-related disease or disorder.Type: GrantFiled: April 6, 2011Date of Patent: October 22, 2013Assignee: Anthrogenesis CorporationInventors: James W. Edinger, Steven Alan Fischkoff, Aleksandar Francki, Vladimir Jankovic, Bitao Liang, Philippe Martin, Cynthia Ray, Xiaokui Zhang
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Patent number: 8367409Abstract: Provided herein are novel angiogenic cells from amnion, referred to as amnion derived adherent cells, and populations of, and compositions comprising, such cells. Further provided herein are methods of obtaining such cells and methods of using the cells in the treatment of individuals.Type: GrantFiled: November 19, 2009Date of Patent: February 5, 2013Assignee: Anthrogenesis CorporationInventors: Stewart Abbot, James W. Edinger, Aleksandar Francki, Aleksandr Kaplunovsky, Vladimir Jankovic, Kristen Labazzo, Eric Law, Neerav D. Padliya, Jennifer Paredes, Jia-Lun Wang
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Publication number: 20120201787Abstract: Provided herein are methods of treating spinal cord and traumatic brain injuries using cells from amnion, and populations of such cells, referred to herein as “amnion derived adherent cells” (“AMDACs”).Type: ApplicationFiled: December 15, 2011Publication date: August 9, 2012Inventors: Stewart Abbot, James W. Edinger, Aleksandar Francki, Vladimir Jankovic, Aleksandr Kaplunovsky, Kristen Labazzo, Eric Law, Bitao Liang
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Publication number: 20120164114Abstract: Provided herein are methods of using amnion derived adherent cells, and populations of, and compositions comprising, such cells, in the modulation of an immune response. In various embodiments, the immune response is graft-versus-host disease, an allergy, asthma, or an immune-related disease or disorder, e.g., an autoimmune disease.Type: ApplicationFiled: December 15, 2011Publication date: June 28, 2012Inventors: Stewart Abbot, James W. Edinger, Aleksandar Francki, Vladimir Jankovic, Bitao Liang
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Publication number: 20120156230Abstract: Provided herein are methods of treatment of individuals having an injury to the central nervous system, such as a spinal cord injury or a traumatic brain injury, using placental stem cells and placental multipotent stem cells described herein, and populations of such placental cells.Type: ApplicationFiled: December 15, 2011Publication date: June 21, 2012Inventors: Stewart Abbot, James W. Edinger, Aleksandar Francki, Vladimir Jankovic, Aleksandr Kaplunovsky, Kristen Labazzo, Eric Law, Bitao Liang
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Publication number: 20110250182Abstract: Provided herein are methods of treating individuals having diseases or disorders of the circulatory system, using placental cells, e.g., the placental stem cells and placental multipotent cells (PDACs) described herein, and populations of such placental cells. The invention also provides methods of angiogenesis using such cells or populations of cells comprising such cells.Type: ApplicationFiled: April 6, 2011Publication date: October 13, 2011Applicant: ANTHROGENESIS CORPORATIONInventors: Stewart ABBOT, James W. EDINGER, Aleksandar FRANCKI, Robert J. HARIRI, Vladimir JANKOVIC, Aleksandr KAPLUNOVSKY, Kristen LABAZZO, Eric LAW, Neerav D. PADLIYA, Jennifer PAREDES, Jia-Lun WANG
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Publication number: 20100311166Abstract: The invention relates to the discovery that the proliferation and survival of pancreatic progenitor cells can be enhanced by contacting the cells with, (1) a caspase inhibitor sufficient to reduce apoptosis in the pancreatic endocrine cells; and, (2) a growth factor in an amount sufficient to increase the level of activated Akt in the pancreatic endocrine cells.Type: ApplicationFiled: January 18, 2007Publication date: December 9, 2010Applicant: ReNeuron, Inc.Inventors: Monica Florio, Aleksandar Francki, Wen-Ghih Tsang
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Publication number: 20100124569Abstract: Provided herein are novel angiogenic cells from amnion, referred to as amnion derived adherent cells, and populations of, and compositions comprising, such cells. Further provided herein are methods of obtaining such cells and methods of using the cells in the treatment of individuals.Type: ApplicationFiled: November 19, 2009Publication date: May 20, 2010Inventors: Stewart ABBOT, James W. Edinger, Aleksandar Francki, Aleksandr Kaplunovsky, Vladimir Jankovic, Kristen Labazzo, Eric Law, Neerav D. Padliya, Jennifer Paredes, Jia-Lun Wang