Abstract: A fracture mapping system for use in hydraulic fracturing operations utilizing non-directionally sensitive fiber optic cable, based on distributed acoustic sensing, deployed in an observation well to detect microseismic events and to determine microseismic event locations in 3D space during the hydraulic fracturing operation. The system may include a weighted probability density function to improve the resolution of the microseismic event on the fiber optic cable.

Abstract: A fiber optic cable positioned along a casing string in a wellbore may be calibrated by exciting a tube wave in the wellbore and detecting, by the fiber optic cable, a reflected tube wave. The reflected tube wave may correspond to a reflection of the tube wave off an obstacle within the wellbore. The obstacle may have a known location such that a reference point along the fiber optic cable may be associated with the known location of the obstacle for calibrating the fiber optic cable. Downhole applications utilizing data collected by the calibrated fiber optic cable, including location data, may weight the data collected based at least in part on an uncertainty value associated with a particular calibrated location along the length of the fiber optic cable.

Abstract: A well system includes a fiber optic cable positionable downhole along a length of a wellbore. The well system also includes a reflectometer communicatively coupleable to the fiber optic cable. The reflectometer injects optical signals into the fiber optic cable and receives reflected optical signals from the fiber optic cable. Further, the reflectometer identifies strain detected in the reflected optical signals generated from seismic waves of a microseismic event. Additionally, the reflectometer identifies a focal mechanism of the microseismic event and velocities of the seismic waves. The reflectometer also determines a position of the microseismic event using the strain detected in the reflected optical signals, the focal mechanism of the microseismic event, and the velocities of the seismic waves.

Abstract: A fracture mapping system for use in hydraulic fracturing operations utilizing non-directionally sensitive fiber optic cable, based on distributed acoustic sensing, deployed in an observation well to detect microseismic events and to determine microseismic event locations in 3D space during the hydraulic fracturing operation. The system may include a weighted probability density function to improve the resolution of the microseismic event on the fiber optic cable.

Abstract: A fiber optic cable positioned along a casing string in a wellbore may be calibrated by exciting a tube wave in the wellbore and detecting, by the fiber optic cable, a reflected tube wave. The reflected tube wave may correspond to a reflection of the tube wave off an obstacle within the wellbore. The obstacle may have a known location such that a reference point along the fiber optic cable may be associated with the known location of the obstacle for calibrating the fiber optic cable. Downhole applications utilizing data collected by the calibrated fiber optic cable, including location data, may weight the data collected based at least in part on an uncertainty value associated with a particular calibrated location along the length of the fiber optic cable.

Abstract: A well system includes a fiber optic cable positionable downhole along a length of a wellbore. The well system also includes a reflectometer communicatively coupleable to the fiber optic cable. The reflectometer injects optical signals into the fiber optic cable and receives reflected optical signals from the fiber optic cable. Further, the reflectometer identifies strain detected in the reflected optical signals generated from seismic waves of a microseismic event. Additionally, the reflectometer identifies a focal mechanism of the microseismic event and velocities of the seismic waves. The reflectometer also determines a position of the microseismic event using the strain detected in the reflected optical signals, the focal mechanism of the microseismic event, and the velocities of the seismic waves.

Abstract: The present invention provides methods and liposomal compositions useful in therapeutics, and diagnosis, prognosis, testing, screening, treatment and/or prevention of various disease conditions. The present invention provides imaging methods for various conditions. The present invention is a multi-layered drug delivery pathway, inclusive of nanoparticle liposomal formulations and mechanisms of localized action via unzipping upon delivery to the affected tissue site. The nano-encapsulation methodology allows maximization a potent antioxidant's biocompatibility, increased target cell penetration and uptake, reduced off-target effects and retention of high anti-oxidative activity for promising therapeutic potential.

Abstract: A method for passive seismic imaging includes entering into a programmable computer seismic signals measured at a plurality of spaced apart locations above a volume of Earth's subsurface to be evaluated. The signals are measured at each location along different directions to enable resolution of motion in three orthogonal directions. A seismic moment tensor is determined for at least one seismic event occurring in the subsurface from the measured seismic signals. Divergence-free transverse) and curl-free longitudinal components of a source term are determined from the moment tensor, seismic velocities, and the measured seismic signals. An image is generated at at least one point in the subsurface using the determined components.

Abstract: A pancreatic beta cell stimulation system for stimulating release of insulin from pancreatic beta cells can include an ultrasonic transducer configured to be acoustically coupled to a body of a user; and an ultrasound controller configured to be in communication with the ultrasonic transducer so as to provide control signals to the ultrasonic transducer during operation. The ultrasound controller can be further configured to generate the control signals based on a planned amount of stimulation of pancreatic beta cells within the body of the user such that the control signals instruct the ultrasonic transducer to transmit ultrasound waves having selected intensity and frequency calculated to cause stimulation of the pancreatic beta cells.

Abstract: The present invention provides methods and liposomal compositions useful in therapeutics, and diagnosis, prognosis, testing, screening, treatment and/or prevention of various disease conditions. The present invention provides imaging methods for various conditions. The present invention is a multi-layered drug delivery pathway, inclusive of nanoparticle liposomal formulations and mechanisms of localized action via unzipping upon delivery to the affected tissue site. The nano-encapsulation methodology allows maximization of a potent antioxidant's biocompatibility, increased target cell penetration and uptake, reduced off-target effects and retention of high anti-oxidative activity for promising therapeutic potential.