Patents by Inventor Aleksandar Rajkovic

Aleksandar Rajkovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE THERAPY FOR TREATMENT OF INFERTILITY
    Publication number: 20240082430
    Abstract: Provided are ex vivo and in vivo methods utilizing therapeutic genes for treatment of male and female infertility, including non-obstructive azoospermia (NOA) and premature ovarian insufficiency (POI) and comorbid diseases, with or without transmitting the therapeutic gene to offspring of the infertile subject. Germline gene therapy methods are also described to reduce or eliminate disease from families with or without transmission of the therapeutic gene to offspring.
    Type: Application
    Filed: August 28, 2023
    Publication date: March 14, 2024
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Kyle E. Orwig, Chatchanan Doungkamchan, Alexander N. Yatsenko, Aleksandar Rajkovic
  • OVARIAN-DERIVED HYDROGELS FOR BIOMEDICAL AND BIOTECHNOLOGY APPLICATIONS
    Publication number: 20220395612
    Abstract: The present invention relates to an ovarian-derived hydrogel material, which can be useful for three-dimensional in vitro culturing of cells, cell therapy, fertility preservation, drug delivery, site-specific remodeling and repair of damaged tissue, and/or diagnostic kits.
    Type: Application
    Filed: July 25, 2022
    Publication date: December 15, 2022
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Bryan Brown, Michael Buckenmeyer, Aleksandar Rajkovic, Yonghyun Shin
  • Ovarian-derived hydrogels for biomedical and biotechnology applications
    Patent number: 11458224
    Abstract: The present invention relates to an ovarian-derived hydrogel material, which can be useful for three-dimensional in vitro culturing of cells, cell therapy, fertility preservation, drug delivery, site-specific remodeling and repair of damaged tissue, and/or diagnostic kits.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: October 4, 2022
    Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Bryan Brown, Michael Buckenmeyer, Aleksandar Rajkovic, Yonghyun Shin
  • GENE THERAPY FOR TREATMENT OF INFERTILITY
    Publication number: 20200171171
    Abstract: Provided are ex vivo and in vivo methods utilizing therapeutic genes for treatment of male and female infertility, including non-obstructive azoospermia (NOA) and premature ovarian insufficiency (POI) and comorbid diseases, with or without transmitting the therapeutic gene to offspring of the infertile subject. Germline gene therapy methods are also described to reduce or eliminate disease from families with or without transmission of the therapeutic gene to offspring.
    Type: Application
    Filed: July 26, 2018
    Publication date: June 4, 2020
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Kyle E. Orwig, Chatchanan Doungkamchan, Alexander N. Yatsenko, Aleksandar Rajkovic
  • OVARIAN-DERIVED HYDROGELS FOR BIOMEDICAL AND BIOTECHNOLOGY APPLICATIONS
    Publication number: 20170252485
    Abstract: The present invention relates to an ovarian-derived hydrogel material, which can be useful for three-dimensional in vitro culturing of cells, cell therapy, fertility preservation, drug delivery, site-specific remodeling and repair of damaged tissue, and/or diagnostic kits.
    Type: Application
    Filed: March 3, 2017
    Publication date: September 7, 2017
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYS TEM OF HIGHER EDUCATION
    Inventors: Bryan Brown, Michael Buckenmeyer, Aleksandar Rajkovic, Yonghyun Shin
  • TEX14 compositions and modulators thereof to alter intercellular bridge development and function
    Publication number: 20060223099
    Abstract: The present invention is related to TEX14 and germ cell intercellular bridges and compositions thereof that can be used to inhibit and/or decrease the activity and/or expression of TEX14 and/or disrupt the formation, function, and/or integrity of the intercellular bridges, including localization of key components to the intercellular bridge, for example. In particular aspects, the methods and compositions are employed for fertility and infertility applications.
    Type: Application
    Filed: March 30, 2006
    Publication date: October 5, 2006
    Applicant: BAYLOR COLLEGE OF MEDICINE
    Inventors: Martin Matzuk, Michael Greenbaum, Aleksandar Rajkovic