Patents by Inventor Aleksander Patrzykat

Aleksander Patrzykat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-endotoxic, antimicrobial cationic peptides, the encoding DNA and methods of use thereof
    Publication number: 20080009445
    Abstract: A novel class of cationic peptides having antimicrobial activity is provided. Exemplary peptides of the invention include KWKSFIKKLTSAAKKVVTTAKPLALIS (SEQ ID NO:3) and KGWGSFFKKAAHVGKHVGKAALTHYL (SEQ ID NO:15). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. Such methods are useful for the treatment of respiratory infections, such as in cystic fibrosis patients. Such methods are further useful for accelerating wound healing.
    Type: Application
    Filed: February 15, 2007
    Publication date: January 10, 2008
    Inventors: Robert Hancock, Monisha Gough, Aleksander Patrzykat, Donald Woods, Xiaoyan Jia
  • Genomic approach to identification of novel broad-spectrum antimicrobial peptides from bony fish
    Publication number: 20060093596
    Abstract: There is provided a method of identifying candidate nucleic acid sequences encoding antimicrobial peptides. The method comprises: identifying an initial peptide of interest; identifying genomic DNA encoding the initial peptide; identifying a flanking sequence on each side of the initial peptide; obtaining primers complementary to the flanking sequences; and, screening a wide range of nucleic acid sequences to identify candidate sequences capable of being amplified using the primers from step e). In some instances the antimicrobial peptide is a hepcidin or a pleurocidin.
    Type: Application
    Filed: August 22, 2003
    Publication date: May 4, 2006
    Inventors: Susan Douglas, Jeffrey Gallant, Aleksander Patrzykat
  • Anti-endotoxic antimicrobial cationic peptides and methods of use therfor
    Patent number: 6818407
    Abstract: A novel class of cationic peptides having antimicrobial activity is provided. Exemplary peptides of the invention include KWKSFIKKLTSAAKKVVTTAKPLALIS (SEQ ID NO:3) and KGWGSFFKKAAHVGKHVGKAALTHYL (SEQ ID NO:15). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. Such methods are useful for the treatment of respiratory infections, such as in cystic fibrosis patients. Such methods are further useful for accelerating wound healing.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: November 16, 2004
    Assignee: The University of British Columbia
    Inventors: Robert E. W. Hancock, Monisha A. Gough, Aleksander Patrzykat, Donald Woods, Xiaoyan Jia
  • Anti-endotoxic, antimicrobial cationic peptides and methods of use therefor
    Publication number: 20040186272
    Abstract: A novel class of cationic peptides having antimicrobial activity is provided. Exemplary peptides of the invention include KWKSFIKKLTSAAKKVVTTAKPLALIS (SEQ ID NO:3) and KGWGSFFKKAAHVGKHVGKAALTHYL (SEQ ID NO:15). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. Such methods are useful for the treatment of respiratory infections, such as in cystic fibrosis patients. Such methods are further useful for accelerating wound healing.
    Type: Application
    Filed: April 12, 2004
    Publication date: September 23, 2004
    Inventors: Robert E. W. Hancock, Monisha A. Gough, Aleksander Patrzykat, Donald Woods, Xiaoyan Jia
  • Anti-endotoxic antimicrobial cationic peptides and methods of use therfor
    Publication number: 20030096949
    Abstract: A novel class of cationic peptides having antimicrobial activity is provided. Exemplary peptides of the invention include KWKSFIKKLTSAAKKVVTTAKPLALIS (SEQ ID NO:3) and KGWGSFFKKAAHVGKHVGKAALTHYL (SEQ ID NO:15). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. Such methods are useful for the treatment of respiratory infections, such as in cystic fibrosis patients. Such methods are further useful for accelerating wound healing.
    Type: Application
    Filed: July 17, 2001
    Publication date: May 22, 2003
    Applicant: University of British Columbia
    Inventors: Robert E. W. Hancock, Monisha A. Gough, Aleksander Patrzykat, Donald Woods, Xiaoyan Jia
  • Anti-endotoxic, antimicrobial cationic peptides and methods of use therefor
    Patent number: 6288212
    Abstract: A novel class of cationic peptides having antimicrobial activity is provided. Exemplary peptides of the invention include KWKSFIKKLTSAAKKVVTTAKPLALIS (SEQ ID NO: 3) and KGWGSFFKKAAHVGKHVGKAALTHYL (SEQ ID NO: 15). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. Such methods are useful for the treatment of respiratory infections, such as in cystic fibrosis patients. Such methods are further useful for accelerating wound healing.
    Type: Grant
    Filed: August 28, 1998
    Date of Patent: September 11, 2001
    Assignee: The University of British Columbia
    Inventors: Robert E. W. Hancock, Monisha A. Gough, Aleksander Patrzykat, Donald Woods, Xiaoyan Jia