Patents by Inventor Aleksander Sieron

Aleksander Sieron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant C-proteinase and processes, methods and uses thereof
    Patent number: 6562613
    Abstract: The present invention is directed to the isolation and identification of the nucleic acid sequence encoding C-proteinase, the recognition of such protein's activity and applications, and tools, processes, and methods of use thereof.
    Type: Grant
    Filed: May 7, 2001
    Date of Patent: May 13, 2003
    Assignee: Thomas Jefferson University
    Inventors: Darwin J. Prockop, Yoshio Hojima, Shi-Wu Li, Aleksander Sieron
  • SYNTHESIS OF HUMAN PROCOLLAGENS AND COLLAGENS IN RECOMBINANT DNA SYSTEMS
    Publication number: 20020098578
    Abstract: The invention is transfected cells, substantially all of which contain at least one human collagen gene and express fibrillar collagen molecules derived using methods for synthesizing collagen and collagen fibrils in said cell lines, and methods for treatment of disorders in humans using said collagen derived from said stable cell lines.
    Type: Application
    Filed: February 22, 1999
    Publication date: July 25, 2002
    Inventors: DARWIN J. PROCKOP, LEENA ALA-KOKKO, ANDRZEJ FERTALA, ALEKSANDER SIERON, KARI I. KIVIRIKKO, AMY GEDDIS, TAINA PIHLAJANIEMI
  • Recombinant C-proteinase and processes, methods and uses thereof
    Publication number: 20020037574
    Abstract: The present invention is directed to the isolation and identification of the nucleic acid sequence encoding C-proteinase, the recognition of such protein's activity and applications, and tools, processes, and methods of use thereof.
    Type: Application
    Filed: May 7, 2001
    Publication date: March 28, 2002
    Applicant: Thomas Jefferson University
    Inventors: Darwin J. Prockop, Yoshio Hojima, Shi-Wu Li, Aleksander Sieron
  • Recombinant C-proteinase and processes, methods and uses thereof
    Patent number: 6258584
    Abstract: The present invention is directed to the isolation and identification of the nucleic acid sequence encoding C-proteinase, the recognition of such protein's activity and applications, and tools, processes, and methods of use thereof.
    Type: Grant
    Filed: June 10, 1997
    Date of Patent: July 10, 2001
    Assignee: Thomas Jefferson University
    Inventors: Darwin J. Prockop, Yoshio Hojima, Shi-Wu Li, Aleksander Sieron
  • Recombinant C-proteinase and processes, methods and uses thereof
    Patent number: 6020193
    Abstract: The present invention is directed to the isolation and identification of the nucleic acid sequence encoding C-proteinase, the recognition of such protein's activity and applications, and tools, processes, and methods of use thereof.
    Type: Grant
    Filed: August 26, 1998
    Date of Patent: February 1, 2000
    Assignee: FibroGen, Inc.
    Inventors: Darwin J. Prockop, Yoshio Hojima, Shi-Wu Li, Aleksander Sieron
  • Synthesis of human procollagens and collagens in recombinant DNA systems
    Patent number: 5593859
    Abstract: The invention is transfected cells, substantially all of which contain at least one human collagen gene and express fibrillar collagen molecules derived using methods for synthesizing collagen and collagen fibrils in said cell lines, and methods for treatment of disorders in humans using said collagen derived from said stable cell lines.
    Type: Grant
    Filed: August 11, 1994
    Date of Patent: January 14, 1997
    Assignee: Thomas Jefferson University
    Inventors: Darwin J. Prockop, Leena Ala-Kokko, Andrzej Fertala, Aleksander Sieron, Kari I. Kivirikko, Amy Geddis, Taina Pihlajaniemi
  • Synthesis of human procollagens and collagens in recombinant DNA systems
    Patent number: 5405757
    Abstract: The invention is stably transfected cells, substantially all of which contain at least one human collagen gene and express fibrillar collagen molecules derived using methods for synthesizing collagen and collagen fibrils in said cell lines, and methods for treatment of disorders in humans using said collagen derived from said stable cell lines.
    Type: Grant
    Filed: March 24, 1993
    Date of Patent: April 11, 1995
    Assignee: Thomas Jefferson University
    Inventors: Darwin J. Prockop, Leena Ala-Kokko, Andrzej Fertala, Aleksander Sieron, Kari I. Kivirikko, Amy Geddis