Abstract: An elongate embolectomy device having a radially constrained configuration and a radially expanded configuration, the embolectomy device being formed out of a plurality of elongate clot engaging structures, each clot engaging structure comprising a plurality of interconnected struts forming an open cell pattern, wherein, when the embolectomy device is in the radially expanded configuration, the clot engaging structures each have a semi-tubular arcuate profile, including a convex face and an concave face facing opposite the convex face, extending along a length of the embolectomy device, the clot engaging structures being longitudinally disposed relative to each other such that the concave faces are facing radially outward, and the convex surfaces are facing radially inward, respectively, relative to a longitudinal axis of the embolectomy device.

Abstract: A method of assembling an apparatus for delivering an implant to a deployment site in a patient's vasculature, includes: positioning an implant engagement member at least partially within a lumen of a tubular structure, the tubular structure having a sidewall comprising a pattern of wires or struts; heating the implant engagement member; pressing at least a portion of the sidewall of the tubular structure radially inward into a surface of the implant engagement member so that the wires or the struts of the sidewall penetrate into the surface and create corresponding recesses therein; and after the recesses are created in the surface of the implant engagement member, hardening the implant engagement member.

Abstract: An elongate embolectomy device having a radially constrained configuration and a radially expanded configuration, the embolectomy device being formed out of a plurality of elongate clot engaging structures, each clot engaging structure comprising a plurality of interconnected struts forming an open cell pattern, wherein, when the embolectomy device is in the radially expanded configuration, the clot engaging structures each have a semi-tubular arcuate profile, including a convex face and an concave face facing opposite the convex face, extending along a length of the embolectomy device, the clot engaging structures being longitudinally disposed relative to each other such that the concave faces are facing radially outward, and the convex surfaces are facing radially inward, respectively, relative to a longitudinal axis of the embolectomy device.

Abstract: An elongate embolectomy device having a radially constrained configuration and a radially expanded configuration, the embolectomy device being formed out of a plurality of elongate clot engaging structures, each clot engaging structure comprising a plurality of interconnected struts forming an open cell pattern, wherein, when the embolectomy device is in the radially expanded configuration, the clot engaging structures each have a semi-tubular arcuate profile, including a convex face and an concave face facing opposite the convex face, extending along a length of the embolectomy device, the clot engaging structures being longitudinally disposed relative to each other such that the concave faces are facing radially outward, and the convex surfaces are facing radially inward, respectively, relative to a longitudinal axis of the embolectomy device.

Abstract: A guidewire includes: a shaft having a proximal end, a distal end, and a body extending from the proximal end to the distal end; a blunt tip; and a sleeve; wherein the body of the shaft comprises at least a segment that is surrounded by the sleeve, the segment coupled to the blunt tip; and wherein the segment of the body of the shaft comprises a flat portion having one or more openings extending through a thickness of the flat portion.

Abstract: A thromboembolic removal system for treating ischemic stroke, including a guide and occlusion catheter, a delivery and aspiration catheter, an aspiration pump, a thromboembolic receiver, and a thromboembolic separator.

Abstract: An embolectomy device includes a pair of elongate spine members extending in a substantially parallel configuration along a longitudinal axis of the device, a first plurality of clot engaging structures having first ends attached to a first one of the spine members and second ends attached to other one of the spine members, and a second plurality of clot engaging structures having first and second ends attached to the respective first and second spine members offset 180° from the first plurality of attached clot engaging structures, such that, when the embolectomy device is unsheathed within in a blood vessel alongside a clot, one of the first and second plurality of the clot engaging structures contact and compress against a wall of the blood vessel to provide a biasing force to facilitate engagement of the other one of the first and second plurality of the clot engaging structures with the clot.

Abstract: An embolectomy device includes a pair of elongate spine members extending in a substantially parallel configuration along a longitudinal axis of the device, a first plurality of clot engaging structures having first ends attached to a first one of the spine members and second ends attached to other one of the spine members, and a second plurality of clot engaging structures having first and second ends attached to the respective first and second spine members offset 180° from the first plurality of attached clot engaging structures, such that, when the embolectomy device is unsheathed within in a blood vessel alongside a clot, one of the first and second plurality of the clot engaging structures contact and compress against a wall of the blood vessel to provide a biasing force to facilitate engagement of the other one of the first and second plurality of the clot engaging structures with the clot.

Abstract: An elongate embolectomy device having a radially constrained configuration and a radially expanded configuration, the embolectomy device being formed out of a plurality of elongate clot engaging structures, each clot engaging structure comprising a plurality of interconnected struts forming an open cell pattern, wherein, when the embolectomy device is in the radially expanded configuration, the clot engaging structures each have a semi-tubular arcuate profile, including a convex face and an concave face facing opposite the convex face, extending along a length of the embolectomy device, the clot engaging structures being longitudinally disposed relative to each other such that the concave faces are facing radially outward, and the convex surfaces are facing radially inward, respectively, relative to a longitudinal axis of the embolectomy device.

Abstract: An aneurysm occlusion system includes a device positionable within a cerebral blood vessel covering a neck of an aneurysm on the blood vessel. The device includes an expandable tubular element having a lumen surrounded by a sidewall including a plurality of gaps. When expanded, the tubular element includes longitudinal standards arrayed helically in a proximal to distal direction. The standards support struts and the gaps are defined between adjacent struts and are sufficiently large to permit delivery of embolic coils or other embolic materials therethrough.

Abstract: An aneurysm occlusion system includes a device positionable within a cerebral blood vessel covering a neck of an aneurysm on the blood vessel. The device includes an expandable tubular element having a lumen surrounded by a sidewall including a plurality of gaps. When expanded, the tubular element includes longitudinal standards arrayed helically in a proximal to distal direction. The standards support struts and the gaps are defined between adjacent struts and are sufficiently large to permit delivery of embolic coils or other embolic materials therethrough.

Abstract: A highly compressible stent is described. The stent includes a plurality of circumferentially offset and interconnected undulating rings having intermediate struts disposed between at least some of the undulating ring struts.

Abstract: Treatment devices having a self-expandable member with one or more of a proximal end portion, a main body portion and a distal portion. According to some implementations a self-expandable member is provided with proximal end portion comprising a peripheral rail having a first substantially straight segment and a second substantially straight segment that extends distally to the first substantially straight segment with the angular orientation of the second substantially straight segment being different than the angular orientation of the first substantially straight segment, the angular orientation of the second substantially straight segment being similar to a helix angle of at least some of the cell structures in the main body portion.

Abstract: An aneurysm occlusion system includes a device positionable within a cerebral blood vessel covering a neck of an aneurysm on the blood vessel. The device includes an expandable tubular element having a lumen surrounded by a sidewall including a plurality of gaps. When expanded, the tubular element includes longitudinal standards arrayed helically in a proximal to distal direction. The standards support struts and the gaps are defined between adjacent struts and are sufficiently large to permit delivery of embolic coils or other embolic materials therethrough.

Abstract: A system for restoring blood flow through an occluded vessel in the cerebrovasculature is disclosed. The system includes a tubular element constructed of shape memory material eccentrically mounted on the distal end of an introducer. The walls of the tubular element are defined by standards and connectors, and the standards are oriented at an angle to the longitudinal axis of the tubular element. A method of manufacture of the system includes cutting a tube of shape memory material, conferring a twist on the cut tube, and heat setting the tube. The method further includes affixing the shape set tube to an introducer. A method of treatment using the system is also described.

Abstract: An aneurysm occlusion device is positionable within a cerebral blood vessel covering a neck of an aneurysm on the blood vessel. The device includes a tubular element having a lumen surrounded by an occlusive sidewall including a plurality of gaps. The gaps are sufficiently small to cause at least partial occlusion against flow of blood from the blood vessel through the side wall into the aneurysm, but are expandable in response to a fluid pressure differential between a first area inside the lumen and a second area outside the lumen to allow flow of fluid through the side wall between the blood vessel and a side branch vessel.