Patents by Inventor Aleksandr Nivorozhkin

Aleksandr Nivorozhkin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage
    Publication number: 20050201943
    Abstract: The present invention relates to contrast agents for diagnostic magnetic resonance imaging. In particular, this invention relates to novel compounds which exhibit surprisingly improved relaxivity due to improved binding of an amino acid targeting group within the molecules to proteins following specific cleavage of the agent by a peptidase. This invention also relates to pharmaceutical compositions comprising these compounds and to methods of using the compounds and compositions for contrast enhancement during magnetic resonance imaging.
    Type: Application
    Filed: May 2, 2005
    Publication date: September 15, 2005
    Inventors: Aleksandr Nivorozhkin, Thomas McMurry, Andrew Kolodziej
  • Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage
    Publication number: 20030082106
    Abstract: The present invention relates to contrast agents for diagnostic magnetic resonance imaging. In particular, this invention relates to novel compounds which exhibit surprisingly improved relaxivity due to improved binding of an amino acid targeting group within the molecules to proteins following specific cleavage of the agent by a peptidase. This invention also relates to pharmaceutical compositions comprising these compounds and to methods of using the compounds and compositions for contrast enhancement during magnetic resonance imaging.
    Type: Application
    Filed: July 19, 2002
    Publication date: May 1, 2003
    Inventors: Aleksandr Nivorozhkin, Thomas J. McMurry, Andrew Kolodziej